ID A4YPN2_BRASO Unreviewed; 1154 AA.
AC A4YPN2;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN OrderedLocusNames=BRADO2000 {ECO:0000313|EMBL:CAL75858.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL75858.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL75858.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. {ECO:0000256|HAMAP-
CC Rule:MF_01894}.
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DR EMBL; CU234118; CAL75858.1; -; Genomic_DNA.
DR RefSeq; WP_011925080.1; NC_009445.1.
DR AlphaFoldDB; A4YPN2; -.
DR STRING; 114615.BRADO2000; -.
DR KEGG; bra:BRADO2000; -.
DR eggNOG; COG1196; Bacteria.
DR HOGENOM; CLU_001042_2_3_5; -.
DR OrthoDB; 9808768at2; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977:SF2; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994}.
FT DOMAIN 3..1135
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT DOMAIN 507..545
FT /note="SMC hinge"
FT /evidence="ECO:0000259|Pfam:PF06470"
FT REGION 454..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 170..197
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 644..713
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 748..990
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1154 AA; 127270 MW; A5F32481783F963E CRC64;
MKLTRLRLHG FKTFVEPTDF VIEPGLTGVV GPNGCGKSNL VEALRWAMGE TSHKSLRAAD
MDAVIFSGSN TRPSRNHAEV VMTIDNSDRT APAAVNDRDI LEISRRIERE AGSVYRINGR
DVRARDVQIL FADAATGARS PALVHQGKIG EIIQAKPEQR RRVLEDAAGV AGLHARRHEA
ELRLKAAETN LLRVEDVIGQ LSGQMEGLRK QARQAIRYRE VAAKVRKAEA TLYHLRWMGA
HADLNDAAHT HDVAVREMAE RTREQAESAR IQAIRSSHLP ALREAEARAA ATMQRLKNAR
DLLDREEVRA KERAGELDRR LMQLTADVAR EQQQNQDAQV ALQRLETEDA ELKEEIKARV
EMRSGVDERV AEAEALLLET ERQFTELTTQ LADLTARRNQ LEANVRSHRE RLARLDQDIA
NVRADEERLA QETAHLGDLD TLAAALEAAE EAEAQAEAAV QTNEAAQANA RQKLEASRAP
LADAEKRAQR LETEARTISK MVNSETKNLW PPIIDGVTVA KGYEKALGAV LGDDLDAPVD
ASAPMHWTVA GAEVTDPALP DGVEPLAAYV QAPPELSRRL AQIGVVSRER GAQLVSQLRT
GQRLVSPEGD VWRWDGFIAA AHAPTGAARR LAERARLIDI EAELEQARID AAGKRQALES
AEAEVKAATA AESAAREAWR AAQREVNSAR ERHANAEREI NRHSARKSAL VEASTRLAHD
RAEIAELHQN ALEAIEELPA TTEADGRLAA VRAEIETKRR AAAQVRAEAQ ALAREAELAD
RRVQAIINER NDWFNRIRGA GSQIATIEAR IAEVRDERAE LDNAPEIFAE KRSALIDELA
IAEEERQVAA DALAEAETAM GDTDRAAKAS LEALSKSREA AARAEERLES AKRRVADVER
EIHDMLECEP NAVAAMAEIG PDTQLPPLHE IEDSLEKLRR DRERLGAVNL RAEEELTEVE
GSHTALTTER DDLVEAIKRL RQGIQSLNKE ARERLQASFE TVNDHFKRLF TELFGGGEAA
LHLIESDDPL EAGLEIIAKP PGKKPQTLSL LSGGEQALTA MALIFAVFLT NPSPICVLDE
VDAPLDDHNV ERFCNLLHEM KGSTETRFII ITHNPITMAR MNRLFGVTMA ERGVSQLVSV
ALDEAVKILD QQVA
//
