ID A4YPX0_BRASO Unreviewed; 670 AA.
AC A4YPX0;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=BRADO2089 {ECO:0000313|EMBL:CAL75946.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL75946.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL75946.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CU234118; CAL75946.1; -; Genomic_DNA.
DR RefSeq; WP_011925167.1; NC_009445.1.
DR AlphaFoldDB; A4YPX0; -.
DR STRING; 114615.BRADO2089; -.
DR KEGG; bra:BRADO2089; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_000445_114_71_5; -.
DR OrthoDB; 9789238at2; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:CAL75946.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994};
KW Transferase {ECO:0000313|EMBL:CAL75946.1}.
FT DOMAIN 103..155
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 241..292
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 369..422
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 440..668
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 413..440
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 670 AA; 74368 MW; B90D7CFA995A0F53 CRC64;
MISREFGRTF WRNQTSVDYA LADLAAGRLE DHDFRLLADG IPTLCWIANG DGYIVWYNRR
WHEYCGSTPT QMEGWGWQSV HDPAQLPSVM QRWQASIATG EPFEMTFPLR GADGVFRPFL
TRIQPMRDAS GRIRRWFGVN TEVSAQVQAE QALRDSETQA RADAERIQLA LAAGAIIGTW
VWDIPANRFT IDENFAVNFG LDPALGREGL SLEQVTMTVH PDDQAGLAAA IQDALTRGGD
YAHQYRVRRR DGRYHWIEAN GRVELRDGKP VRFPGVLLDV NARHAAEAAL RETEERLRLA
TQVAEIGFWD YDPATGVLIW PPLVRAMFGV AEDVPVTIAD FYEGLHPDDR EPTTAAFAAA
ADPAQRALYD VEYRTIGKND GALRWVAAKG RGLFDEAGHC VRLIGTAIDI TARKTAEARL
RDLNERLEVA NEEIKRYAHV VSHDLRAPLV NIMGFAQELQ SQRDEMFAAG QLPKADPQRV
QAERDFDESL SFIRAATQKM DGLITAILKV SRHGQQPLHP EPLDMEALVR KLADAIRHQT
ETAGAVITIE PLPSLVADPL AVGQIFGNLL DNAVKYLDPD RPGRITVSGE ARGREVVVHV
ADNGRGIRPE DQARVFELFQ RAGQRDQPGE GIGLAHVKSL VGRMHGNISL TSEAGVGTTF
TVTLPRTPAN
//
