ID A4YRP8_BRASO Unreviewed; 567 AA.
AC A4YRP8;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Calpain catalytic domain-containing protein {ECO:0000259|PROSITE:PS50203};
GN OrderedLocusNames=BRADO2763 {ECO:0000313|EMBL:CAL76574.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL76574.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL76574.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
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DR EMBL; CU234118; CAL76574.1; -; Genomic_DNA.
DR RefSeq; WP_011925779.1; NC_009445.1.
DR AlphaFoldDB; A4YRP8; -.
DR STRING; 114615.BRADO2763; -.
DR KEGG; bra:BRADO2763; -.
DR eggNOG; COG1572; Bacteria.
DR HOGENOM; CLU_480352_0_0_5; -.
DR OrthoDB; 7325981at2; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR PANTHER; PTHR10183; CALPAIN; 1.
DR PANTHER; PTHR10183:SF379; CALPAIN-A-RELATED; 1.
DR Pfam; PF00648; Peptidase_C2; 1.
DR SMART; SM00230; CysPc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50203; CALPAIN_CAT; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00239};
KW Protease {ECO:0000256|PROSITE-ProRule:PRU00239};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994};
KW Thiol protease {ECO:0000256|PROSITE-ProRule:PRU00239}.
FT DOMAIN 254..477
FT /note="Calpain catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50203"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 268
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 449
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 467
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
SQ SEQUENCE 567 AA; 57804 MW; CD7AC5CC2A6DD79B CRC64;
MPIQPQGLRK PQTDQTSDQT GVFETDSWLT PDLTQLWLAT QAPVAAPAAA PASDPSEAIA
IYGNFCSVAA TVTTAPSSTS SGSTVTSTST VTATSTTKTP VPSWVNTLTN AAIKADMTAA
ITNGTVTYAG LLKVFTDIDA SLAATKTKLS ASQFADLKTI AANLNNGVST SSYLTYITQA
FVNGNAANAT WTGGAASSVA LGNLASGSTE LQFAELIGKW FLGTDLPSSK VILGSTQFSV
SYSNSTKALF GASGASMSDI NQGYLGDCYL LAGLAEVAYK EQSVISSMFT ANGNNTYGVR
FYVNGTARYV TVNTSLANGG TIFNNGGNAI WASLAEKAYA ELQASGVYTG NSINYGNSYT
TIGNGGAPEI ALEAITGASQ ITDFRAMGGS WGKVVYNSSF GVTSYTTGNA TSGVLATIAA
SLAAGDDVIL SSYTNAKDAT GKTTLVASHA MSIYGYNSAN GMLQVRNPWG SAAGQYWQTT
FEVSLATLLA AGDTITIDNV GDAKKVAAAT TTTSSGLKLT SDVNDLAGAA SGFVQAIASL
TDGGSSNVAF TQGLASQQHT LAMPMAA
//
