ID A4YWF6_BRASO Unreviewed; 296 AA.
AC A4YWF6;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Putative transcriptional regulatory protein, LysR family {ECO:0000313|EMBL:CAL78232.1};
GN OrderedLocusNames=BRADO4494 {ECO:0000313|EMBL:CAL78232.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL78232.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL78232.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC encode other nodulation proteins. NodD is also a negative regulator of
CC its own expression. Binds flavonoids as inducers.
CC {ECO:0000256|ARBA:ARBA00003502}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CU234118; CAL78232.1; -; Genomic_DNA.
DR RefSeq; WP_011927342.1; NC_009445.1.
DR AlphaFoldDB; A4YWF6; -.
DR STRING; 114615.BRADO4494; -.
DR KEGG; bra:BRADO4494; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_1_5; -.
DR OrthoDB; 8479357at2; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08442; PBP2_YofA_SoxR_like; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF40; HTH-TYPE TRANSCRIPTIONAL REGULATOR GLTR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 296 AA; 31570 MW; 8FC744DF8EB98C61 CRC64;
MELSDLQTFA AVARTGGITR AAEVLNTVQS NVTQRIKALE AEIGTPLFDR HSRGMTLTGA
GQRLLPYADR MAALSREAVL AARDDGEPRG PLMIGSMETT AAVRLPMRLA DFHRRFPAVA
LSLRTAPTSD LVAGVLDGTL DGAFVAGPID HPELSGIVAF EEELVLVTAR RFESLSSLRA
ATAASGPTAL VFRTGCTYRQ RLEQVFNDFG WPAASRIELG TLDGMIGCVA AGMGVALLPR
AVATRHEMSG SIGLHALDPT HAQVKTLFIH RRAARRSSAL SAFIAGLSRR DRDIAA
//
