ID A5AKA0_VITVI Unreviewed; 928 AA.
AC A5AKA0;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Subtilisin-like protease SBT3.6 {ECO:0008006|Google:ProtNLM};
GN ORFNames=VITISV_018392 {ECO:0000313|EMBL:CAN80173.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN80173.1};
RN [1] {ECO:0000313|EMBL:CAN80173.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; AM428692; CAN80173.1; -; Genomic_DNA.
DR AlphaFoldDB; A5AKA0; -.
DR ExpressionAtlas; A5AKA0; baseline.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 2.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF820; SUBTILISIN-LIKE PROTEASE; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 2.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..37
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 38..928
FT /note="Subtilisin-like protease SBT3.6"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002679304"
FT DOMAIN 41..119
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 145..591
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 669..758
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT DOMAIN 853..915
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT ACT_SITE 154
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 231
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 554
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 928 AA; 99781 MW; B117FA92AD288E8A CRC64;
MSSLSLQKKS SSALWFVIVS VLLILHDQVF FPAAVDAKSN VYIVYMGERQ HGNLDLITDG
HHRMLSEVLG SDEASVESMV YSYKHGFSGF AAKLTEAQAQ MFAELPDVVQ VIPNRLHKLQ
TTRSWDYLGL PLDSPTSLLH ETKMGDGTII GLLDTGIWPE SEVFSEKGLG PIPSRWNGVC
ESGELFHGAK ACNRKLIGAR YLIKGLEAEI GQPFNTTENP DYLSPRDWLG HGTHTSTIAG
GSSVHNVSYN GLGLGTVRGG APRARLAMYK VCWNLYGGVC ADADIFKGID EAIHDGVDVL
SLSISSDIPL FSHVDQHDGI SIASFHAVVR GIPVVSAAGN SGPSAETVSN TAPWIITVAA
STMDRLFATH ITLGNNQTIT GEAVYLGKDT GFTNLAYPEV SDLLAPRYCE SLLPNDTFAA
GNVVLCFTSD SSHIAAESVK KAGGLGVIVA SNVKNDLSSC SQNFPCIQVS NEIGARILDY
IRSTRHPQVR LSPSRTHLGN PVPTKVASFS SRGPSSIAPA ILKPDIAGPG FQILGAEPSF
VPTSTKYYLM SGTSMATPHV SGAVALLRAL NREWSPAAIK SAIVTTAWTT DPSGEPVFAE
GQPMKLADPF DFGGGILNPN GAGNPGLVYD MGKDDCILYL CAMGYNNSAI AKVTGRPTSC
PCNRPSILDV NLPSITIPNL QYSVSLTRSV TNVGAVDSEY NAVIDPPPGV TIKLEPDRLV
FNSKIRTITF RVMVSSARRV STGFSFGSLA WSDGEHAIYA DFRPKYQPKF RVVSRIRTGP
ALLQSGSSPA VGSVNHQWVA VPDGRKLPLN PRGNFLLTQE EASSYPRLED SNTNLGGGLL
PQFPLIGIST SPVHIVYLGK RQHHDPEFIT NTHHEMLTTV LGSKEASVDS MLYSYRHGFS
GFAAKLTEAQ AQAVSGNLPC HKDYKFYW
//
