ID A5AS08_VITVI Unreviewed; 1629 AA.
AC A5AS08;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=VITISV_027465 {ECO:0000313|EMBL:CAN78232.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN78232.1};
RN [1] {ECO:0000313|EMBL:CAN78232.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
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DR EMBL; AM433448; CAN78232.1; -; Genomic_DNA.
DR EnsemblPlants; Vitvi05g00179_t001; Vitvi05g00179_P001; Vitvi05g00179.
DR Gramene; Vitvi05g00179_t001; Vitvi05g00179_P001; Vitvi05g00179.
DR ExpressionAtlas; A5AS08; baseline and differential.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
FT DOMAIN 1190..1357
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 137..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1629 AA; 186316 MW; 98DD4FC28E856B55 CRC64;
MAPPMKQLLE TMCGGDFMNK NPDEAFQFLD YVAEVSRSWD EPIVKEPSRD RXMNRARASX
VYTLPEGLDV QAKLATVMRR LDDLEAKGVQ EIQIVNDGVT QLCLICKSTE HGVQSCPTLP
AVQDMFTEQA NALGTYKQYS SNSPYSNTYN PGWRNHPNLS WRGGNNGQFQ QQGNRFQGNQ
TNGQQGFQPQ GMPSQNFQQQ HQASSSNASL EDMMREFIQK QDKRNEDQNR INAQTSQELV
DIRTTLSQLA VSLSQEKEKF PAQPQKNPRG VNEVSEVQKE DCNVVITLRN GKEYEGPKLP
ISEDIPARDE PTVEKNVRNE KASEKYEEVI VSKNKMSVSN HLPFPSTMQR XKVGDKTLEI
LEVLKQVKIN IPLLDMIKQV SAYAKFLKDL CTVKRRIKLS KKAFLTEQVX AIIENKAMVK
YKDPSCPTIS VQIGDAFVER ALLDLGASVN LLPYSIYKQL GLGELKATTI TLSLSYRSIK
VPRGVVEDVL VQVEKFYYPV DFVVLDTEPL KNGMNSVPII LGRPFLATAN ALINCRNGLM
QLSFGNMTVE MNVFNLCKQP MDHDDVENEE ACLIEALVQE HTEKLMEENI DEFFSTIXKE
ECVQVATEWK EKYTIQSLNS VENDEESKKE EVEISKPELK PLPHGLKYVY LEANEEKPVV
ISATLTEEQE MKLLKVLKKN KRAIGWSISD LKGINPLICT HHIYLEENAK PVRQPQRRLN
PLMQDVVRNE VLKLLDAGII YPISDSSWVS LTQVVPKKSG ITVMKNDEGE LIPTRLTTGW
RVCIDFRKLN AVTKKDHFPL PFLDQVLEXV AGHDYYCFLD GYXGYFQIAI ALEDQEKTTF
TCPFXTYAYR RMPFGLCNAP TTFQRCMLSI FSDMVERIME VFMDDLTVYG KTFDDCLLNL
KKVLKMCIEK DLVLNWEKCH FMATSGVVLG HIISKEGIQV DPAKIEXISK LPLPTTIKEV
RQFLGHAACQ EAFKRLKSLL TTAPIVRSPN CSLPFELMCD ASDYAVGAVL GQREDGKPYV
VYYAKFNIQI KDKQGVENVV ABHLSRVQVE SHFEEAQIND EFPDDALCAV EKLPWFANIV
NYLATGEFPS EWNMETKKYF LSQAKHYAWD DPYLYKFCPD QIMRRCVPED EQQDILRMCH
EGACGGHFAS RKTSAKILHS GFYWPTMFKD CNTHCKSCPQ CQQLGKINTR YQMPQNHICV
FEVFDCWGLD FMGPFPPSFG NLYILVGVDY VSKWVEAVAC KSNDHKVVLK FLKENIFSRF
GIPRAIISDG GSHFCNKSFS TLLQKYGVRH KVSTPYHPQT NGQAKLANRE IKRILTKVVN
TTRKDWSTKL SDALWAYRTA YKTVLGMSPY RIVYGKACHL PVELEHRAYW AVKKMNFDSD
QAGAIRKYDL NELEAYRNES YECLHNAREK HKFYHDKLIL RREFKQGEKV LLYDSKLHIF
PGKLRSRWNG PYVVKEVFPY GTVTIQNPRT EIYGVTSEWV TIYLLWCHFQ IRHQLVPSMV
SMEKVVESRS KQQVDTCQEV FQVRVEVRDG FIKTRRAHFV MNGSPYYANG FNAYWLMYLA
SDPSQHAKVS AAFRKASSHG LIVARIWVFN DGGYGPFSGS YNQQMSKVVY YQIYSLARRG
GIAAGGFFW
//
