ID   A5AUH8_VITVI            Unreviewed;       990 AA.
AC   A5AUH8;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_023829 {ECO:0000313|EMBL:CAN69399.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN69399.1};
RN   [1] {ECO:0000313|EMBL:CAN69399.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM436090; CAN69399.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5AUH8; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          825..990
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   990 AA;  113601 MW;  629103632D61EC6B CRC64;
     MDVKAMITLR SGKEVELQPP KPHDETDSEK ETEKREKIKG KKKGSSERKE DHDSTVNEDP
     EKIVINGDVM KKHMPPPFPQ ALHGKKGIHN ASEILEVLRQ VKVNIPLLDM IKEVSNYAKF
     LKDLCTIKRG LNVNKKAFLT EQVSAIIQCK SPVKYKDLGC PTISVMIGGK IVEKALLDLG
     GSVNLLPYSV YKQLGLDPIV KETNYVPIIL RRPFLATSNA IINCKNGLMQ LTFGNMTLEL
     NIFYMCKKPI NPEEEEGPEE VCIIDTLVEE HCNQKIQEKL NESLGDPDEG LPKPSDLLAT
     LPPWRRIEEI LPLFNEEKAQ ETVKEETPKL SLKPLPTELE YAYLEENKKC PVIISSSLTT
     PQEECLLEVL RRCKKSIGWK ISDLKGISPL VCTYHIYMEE EVKPVHQPQR RLNPHMQEVV
     QAEVLKLLQV GIIYPISDSP WVSPTQVVPK KSGITLVQND KGEEVATRLT SGWRVCIDYR
     KLNVVTRKDH FPLPFIDQEK TTFTCPFGTY AYRRMPFGLC NAPATFQRCM LSISSEMVER
     IMEVFIDDIT IYGSTFEECL VNLETILNRY IEKDLVKCIE VDKEKMELIV KLPSPTTVKG
     VRQFFGHAGF YRSDFAIGAV LGQREDGKPY VIYNASKILN EAQRNYTTTE KELFAVVFTL
     EKFHAYLVGS FIVVFTDHSA LKYLLTKQDA KARLIRWILL LQEFTLQIKD KKGEENVVAD
     HLPRLAIVHN SHGLPINDDF PEESLMLLED TPWYAHIANY LVTGEVPSEW KAQDRKHFFA
     KIHAYYWEKP FLFKYCVDQI IRKCVPKQEQ QGILSHCHLT RRNQMPMNPI LIVDLFDVWG
     IDFMGPFPMT FDNSYILVGV YYVSKWVEAI LCKHNDHRVV LKFLKENIFS RFGVPKAIIS
     DGGTHFCNKP FETLLAKYGV KHKVATPYHP QTSRQVELAN REIKNILMKV VNMSKRDWFV
     KLHDSLWAYR TAYKTILGMP TSIPKLQNRG
//