ID   A5B2C4_VITVI            Unreviewed;       978 AA.
AC   A5B2C4;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAN78580.1};
GN   ORFNames=VITISV_013552 {ECO:0000313|EMBL:CAN78580.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN78580.1};
RN   [1] {ECO:0000313|EMBL:CAN78580.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM444199; CAN78580.1; -; Genomic_DNA.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          18..215
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   DOMAIN          440..569
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   DOMAIN          724..849
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   978 AA;  111024 MW;  1E003D0AA0B5688A CRC64;
     MKGIHPSIAS HRLNVFSTAR PIRQRIRRFH PERQRVIRNE IDKLLEAGFI REVSYPDWLA
     NVRVCIDYTN LNNACPKDSF PLPRIDQIVD STSGQGMLSF LDAFSGYHQI PMSPDDEEKT
     AFITPHDLYC YKVMPFGLKN AGATYQRLMT KIFKPLIGHS VEVYIGDIVV KSETREQHIL
     HLQEVFHLLR KYGMKLNPSK CAFGVSAGKF LGFMVSQRGI EVSPDQVKAV METPPPRNKK
     ELQRLTGKLV ALGRFIARFT DELRPFFVAI RKAGAHGWTD SCQNTLERIK HCLMQPPILS
     SPIPKEKLYM YLAVSEWAIS AVLFRCPSPK EQKPIYYVSR ALADVETRYS KMELTALALR
     SAAQRLRPYF QAHPVIVLTD QPLRNILHKP DLTGRMLQWA IELSEFGIEF QPRLAMKGQV
     MADFVLEYSQ RPSQHDESVK KEWWTLRVDG ASRSSGSGVG LLLQSPTGEH LEQAIRLGFS
     ASNNEAEYEV ILSRLDLALA LSVSKLQIFS DSQLMVKHVQ EEYEAKDARM ARYLAKVRNT
     LQQFTEWTIE KIKRADNRRA DTLAGIAASL PIKEAILLPI HVQTDPSVSE ISTCNTIEAP
     QADGQEWMYD IIEYIRTGTL PGDLKQAHKV RVQAARFTLI GGHLYKRSFT GPYXRCLGQS
     EAQYVLAELH EGICGNHSGG RSLAHRAYSQ GYYWPTMKKD AAAYVKRCDK CQRYAPIPHM
     PSATKWVEAE AYASIKDKDV TKFVWKNIIC RFGIPQTIIA DNGPQFDSIA FRNFCSELNI
     RNSYSTPRYP QSNGQAEATN KTLIIALKKR LEQAKGKWVE ELPGVLWAYR TTPERPTGNT
     PFALAYGMDA VIPTEIGLPT IRTDAAKQSD ANMELGRNLD WTDEVRESAV IRMADYQQRA
     SAHYNRKVRP RAFKNGTLVL RKVFENTTEV SAGKFQANWE GPYIVSKASN NGAYHLQKLD
     GTPLLRPWNV SNLKQYYQ
//