ID   A5B7B1_VITVI            Unreviewed;      1290 AA.
AC   A5B7B1;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_030993 {ECO:0000313|EMBL:CAN67605.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN67605.1};
RN   [1] {ECO:0000313|EMBL:CAN67605.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM449139; CAN67605.1; -; Genomic_DNA.
DR   ExpressionAtlas; A5B7B1; baseline and differential.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR   Gene3D; 1.20.1280.50; -; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR005174; DUF295.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR025724; GAG-pre-integrase_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR013103; RVT_2.
DR   PANTHER; PTHR42648:SF18; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF03478; DUF295; 1.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF13976; gag_pre-integrs; 1.
DR   Pfam; PF07727; RVT_2; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF81383; F-box domain; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          292..387
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   1290 AA;  147421 MW;  5B307CA0B32A7F6E CRC64;
     MRMTVSNSMR KEKFKYNDIR DLILAKEICR RDAGKTSGSS STLNLETRGR GHFIRQCKSP
     KKKNEDDFAN AVTRENYAAG DFGKVYLADG SALDVVGLGD VRILLPNGFV WLLEKVRHIP
     DLRRNLISVG QLDDEGHVIL FVGGTWKVIK GARVLARGKK TDTLYMTSCP RNTIAVADAS
     TDTSLWHRRL GHMSDKGMKM LLSKGKLPEL KSIDFDMCES CILGKQKKVS FLKTSRTPKA
     EKLELVHTDL WGPSPVTSIG GSRYYITFID DSSRKKWKAM VETETGLKVK CLRSDNGGEY
     IDGEFSEYYA AQGIRMEKTI PRTPQQNGVT ERMNRTLNER ARSMRLHVGL PKTFWADAVS
     TAAYLINRGP SVPMEFRLPK EVWSGKEVKF LHLKVFCCIS YVHIDSDARS KLVAKSKICF
     FIGYGDEKFG YRFWDEQNRK IIRSRNVIFN EQVMYKDRST VVSDVTEIDQ KKSEFVNLDE
     LTESTVQKRG EKDKENVNSQ RYSPVLNYLL LTDGGEPECY DEALQDENSS KWELAMKDEM
     DSLLGNQTWE LIELLVGKKA LHNKWVYRIK NEHDGSKRYK VRLVVKGFQQ KEGIDYTEIF
     SSVVKMSTIR LVLGMVAAEN LHLEQLDVKT AFLHGDLEED LYMIQPEGFI VQGQENLVCK
     LRKSLYGLKQ APRQWYKKFD SFMHRVGFKR CEADHCCYVK SFDNSYIILL LYVDDMLIVG
     SSIEKINNLK KQLSKQFAMK DLGATKPDIA HVVGVVSRFM SRPGKQHWEA VKWILRYLKG
     SLDICLCFTG ASLKLQGYVD VDFAGDIDSR KSTTGFVFTL GDTTISWASN LQKIVTLFTI
     EAEYVAATEP GKEMIWLHGL LDESDSERCA LGRSELLLWR KTDTRVLRPS LTQSSLLPQS
     SIWVPRELLI IQKINQTVMA DWSKMPDDPL KLIAEKLHSV EDYVRFGGVC KSWYSIFEDK
     ECCCPSSKSP WLMLAEKENS EIRGFYSPLS GKVYEIRLPE VVGKWCWGSP YGWLVTIGTD
     LDMCLLNPLT RVQILLPSLR ACPNLNTLID SSTQGSRSKD IFIYKAVLSS APSSPDCAVM
     IIYSDYGRLA FTKPGHQTWT LLESESGPVD DIIYFNGSFL AVNLSWEVWI CDISGSQLKT
     IRFAAAPALQ DVDEIEYEAK YLVESGGEIY MVTRNLYDTA RRDIPYMRTW TFSVLKLDMC
     NKRWEEVENL DHCSFFLGNN HSFSTWASDY PEFRKNSIYF TDDYCGFLNI PRNFDMGIYN
     FQNTQIEHYP VGHDALSMFS APLWIRPSFC
//