ID   A5B7H4_VITVI            Unreviewed;      1239 AA.
AC   A5B7H4;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|Pfam:PF13456};
GN   ORFNames=VITISV_043296 {ECO:0000313|EMBL:CAN76538.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN76538.1};
RN   [1] {ECO:0000313|EMBL:CAN76538.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM449333; CAN76538.1; -; Genomic_DNA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR48387; RNASE H TYPE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR48387:SF1; RNASE H TYPE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
FT   DOMAIN          690..772
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|Pfam:PF13456"
FT   REGION          95..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          348..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1239 AA;  141258 MW;  4DC5A30CC81CCDAB CRC64;
     MQFHHQYRAP PPPRSIRQFS QLRMPLSRAF QRLVEGTLIA PLPPRPPPQQ TPPGYQVDLH
     YAYHQRTGHD INSCAVLRHA IQDLIDHGLV DLGPPGVTTN PLPTHDTGGV PPPPGGPLEK
     SFKERTTRFC TSCTLRRLAY PFGAFWPRLI SHNDDDLHLT GFTFDEVQVV SLQTDSRDTM
     PMSFDQYNNT LVLSMMRDMS YLPGRANIFS LCFPDEDFDY GLIVDSRGRH DGVTFDDAYT
     DEMDMIGISR ILDAIPQRPR SAFDLFGVSM LQIDXDDSIT DVATSSFISV EGASDPVDPP
     LFFYFMSRFV IHYDVMFDGN NNDMSLFEYL PMSQHFPLIA PQAPTTTIHD IHDVGDPNDP
     LSGNSDCDSN SXEMKVTPVS NNAESVDFGT SDQPKELKIG SXLSLDERSK LINLLRSYLD
     VFTWSYEDML GLDPSIVQHH LPILPHDRPV KHKLRRLHPR WSLQILMALE DMEKRSFITE
     WGTYCYRVMP FGLKNAGATD QRAATTLFHD MMHKDVEAYV NDMILNPKKS TFGVTSGKLL
     GHIVSECGIE FDLKKIRVIL NMPTPRTKSE IRGFLSRRLR HYMIEYSIRL IPRWDLLRCL
     FDRPVLTVNG SIVTDHLASL PVSDHRPIDD DFPDEQFVLV ASIXXWCLYF DGGTNQSGFG
     IGILLISPLG DHIPRSIRLT FFYHHWLMNN VIEYEACIIG LKTALDLGVK QLEIHRDSNL
     VIQHTQGILR TREEKLKHYH AYLDLFIDRF DELRYTHLPK VENQFTDALA TLASVIEIPT
     GMTMQPLLIE TRFTSAYCCL IGDIENQVEL PWYHDIHQFL AYDAYPKSAI AKDRRALRQL
     ATGFVISGDA LYRRSSDGML LLCIDQVTID RVMREVHVGV CRPHMRGHML ALCTKMSKMS
     DGDLICVPSS KLHALTSPWP FSAWGVDVIE KVSPKSSSGH EYILSAYRSX TNGVVEAVNK
     NIKKILRKMV ETSRDWSXKL SFALSAYRTS IRTSIGATLF SLVYGMEVVL PVEIEVGSLR
     VALEHQIAKM DWLRARYNQL NLLDENILKV TNHMHAYQKK MVRAFRKRVK PRKFQKDWVR
     ALYDLFLHGS RRYIGSEDWV PLVLSALDHY LHHHSHPTVA CFDLSSLGLC LLVEVQDVDQ
     PPFLEDIEES HNAFSIQPPX QGAYPIPLHD DVNSYMYACG PSPLKRFGID VWDILHIQPR
     FLIQQNASRA CPRSDSSIFI DPAGVYIEAY PMHCHVRVF
//