ID   A5B9S6_VITVI            Unreviewed;      1066 AA.
AC   A5B9S6;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=Disease resistance RPP13-like protein 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_010084 {ECO:0000313|EMBL:CAN74331.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN74331.1};
RN   [1] {ECO:0000313|EMBL:CAN74331.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM451605; CAN74331.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5B9S6; -.
DR   ExpressionAtlas; A5B9S6; baseline and differential.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1253; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1-RELATED; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00369; LRR_TYP; 2.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          9..103
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          199..404
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   COILED          126..165
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1066 AA;  120879 MW;  447EEDCB3065C8D4 CRC64;
     MEIVGEVVLS VSLELLFSKL ASSDLWKYAR QEHVHTELRK WKTRLLEIRE VLDDAEDKQI
     TKQHVKAWLA HLRDLAYDVE DVLDEFGYQV MRRKLVAEGY AASTSKVRKF IPTCCTTFTP
     IQAMRNVKLG SKIEDITRRL EEISAQKAEL GLEKLKVQIE GARAATQSPT PPPPLAFKPG
     VYGRDDDKTK ILAMLNDEFL GGNPSVVSIV AMGGMGKTTL AGLVYDDEET SKHFALKAWV
     CVSDQFHVET ITRAVLRDIA PGNNDSPDFH QIQRKLRDET KGKRFLIVLD DLWNEKYDQW
     DSLRSPLLEG APGSKILVTT RNKNVATMMG GDKNFYELKH LSDNDCWELF KRHAFENRNT
     NEHPDLALIG REIVKKCGGL PLAAKALGGL LRHEHREDKW NIILASKIWN LPGDKCGILP
     ALRLSYNHLP SHLKRCFAYC ALFPQDYEFK KEELILLWMA EGLIQQSNED EKMEDLGDDY
     FCELLSRSFF QSSGSNKSQF VMHDLINDLA NSIAGDTCLH LDDELWNDLQ CPVSENTRHS
     SFICHKYDIF KKCERFHEKE HLRTFIALPI DEQPTWLEHF ISNKVLEELI PRLGHLRVLS
     LAYYKISEIP DSFGKLKHLR YLNLSHTSIK WLPDSIGNLF YLQTLKLSCC EELIRLPISI
     GNLINLRHLD VAGAIKLQEM PIRMGKLKDL RILSNFIVDK NNGLTIKELK DMSHLRGELC
     ISKLENVVNI QDARDADLKS KRNLESLIMQ WSSELDGSGN ERNQMDVLDS LQPCSNLNKL
     CIQLYGGPEF PRWIGGALFS KMVDLSLIDC RKCTSLPCLG QLPSLKQLRI QGMVGVKKVG
     AEFYGETRVS AGKFFPSLES LHFNSMSEWE HWEDWSSSTE SLFPCLHELT IEDCPKLIMK
     LPTYLPSLTK LSVHLCPKLE SPLSRLPLLK ELQVRGCNEA VLSSGNDLTS LTELTISRIS
     GLIKLHEGFV QFFQGLRVLE SLTCLEELTI SDCPKLASFP DVGFVGTSFV CLALGSRMGR
     IPEWPPQDSN PSPRLKDDKV LSCVSKRAAS YNPNKGGDPE LLKFGV
//