ID A5BC00_VITVI Unreviewed; 1884 AA.
AC A5BC00;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=VITISV_007944 {ECO:0000313|EMBL:CAN74381.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN74381.1};
RN [1] {ECO:0000313|EMBL:CAN74381.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM454059; CAN74381.1; -; Genomic_DNA.
DR ExpressionAtlas; A5BC00; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR026961; PGG_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR013103; RVT_2.
DR PANTHER; PTHR24186:SF38; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24186; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13962; PGG; 1.
DR Pfam; PF14223; Retrotran_gag_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF07727; RVT_2; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1755..1776
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1796..1819
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1831..1857
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1863..1881
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 457..623
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REPEAT 1370..1397
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1513..1535
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1581..1603
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1617..1649
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 231..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..840
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1884 AA; 213161 MW; F45B46B8A08AB946 CRC64;
MANPENVLSI QAFHQCSSLV SIKLNMSNLL LWRSQVLPLV RSLGLIHHLS ENRHASXETM
GTETKETHDQ SIETWSHNDG LLTSWLLGLM TEEVMLLLDG TETAYDVWNS LGEKLLPMTK
EKEVQLTNRL RGVKKGTRSL DEYLREFKGI CDALAAVRKP VSDLDKXFQL AQGLGTKYMD
FRVAMLSKPP YPSYNQFVLA LQGHEQMIMT ENEENKESIN HEQAYFTQRG RGRNRGGRFL
SRGRGFTPAG RFNNNATSDQ RQNVYSSTRN PRNSFNNQFP PQQISTRNPR NSFNNQFPPQ
QKLQKSEGTL ICQICSKANH SALDCWNRFD YXYQSEEIPQ ALAAMALHEE EKDPNFYVDS
GATAHITNDP EFSSTGFVIK DQLQQVLARG TKKGGLYALE ENVIQAMTVT RSSKASSEVW
HQRMXHPQTK SIKLLXDKKF IELGKSCKLP FGLRNKISSN PLDKIHCDLW GXAPNNSTQG
YKYYXVFIDD HTRYTWLYPL RRKSDFFECF LKFQILVENQ LERRIKIFQS DGGGEFQSIK
FQNHLSKCGI LQQVSCPGTP EQNGVAERKH RHIVEMGLTM LFNAKLPLSL WVDAFLTAVY
LINRLPSTVL KMESPFFMLF KQYPEYRSLR IFGCQCFPYL RDYGKNKFSP KTYPCVFIGY
SSLHKGYRCL HPSTKRVYIS RHVIFNENCF PYDNSLVKEN HLQIPIEMVS FSTSDASCET
SKIDHQTKSW KENTANQSSN SKKCSHCPCT TEQRNQFSVE GRISARCNTN QNTEASCVNS
TGTPTAVATE ISTVAASKND HNTVVTTETP TDVALGASDH NSHTATTTGT LSQIESTNSY
KPAKKNEHVD PSLQNKSTSX SADDEVLDSS KQIVVDISPP QGQHTDNKGT HMITRSKLKN
DPSLKSQMVT FAXXRSDISE PKTYRTALKI PHWLKAMQEE IKALIQNRTW DLVPRPPTTN
IVGSKWVFKT KLKEDGTIDR YKARLVARGF SQIPGLDFGE TFSPVIKHTT IRMIFSLAVI
LGWKMRQLDV KNAFLHGFLK EEVFMEQPPG FINEVLPNHV CKLNRSLYGL KQAPRAWFDR
LSQCLLHLGF CCGKADSSLF ILRKVNKACQ HFQAPTKADL XAVKRILRYL KGTMEHGIXF
FKQSSLRLTG FCDADWAGCT NTRRSTSGYC IFLGANCISW SSKRQPTVSR SSAEAEYRSL
ASSAAEITWL TFLLRDIGIQ LREPPQLLCD NLSALHMTVN PVFHARSKHI ELDYHFVREK
VARGVLITRF LPSSLQVADI FTKALPKTSF QFFRFKLGVH KWTLPERPIR LNPGLLSQAN
MKGDTPLHTA SRTGCLGMVE QFISSSKALC YDIERIRENE PQDLLMVNQE GDTALHVAVR
YGHLDVVELL VNADIELMLH MYNKANESPL YLAVERGFFA IAKHILNKCP TCSHRGTKGM
TALHAAVVRT HQGHERGNDV PHLISLESLR RFVYNIVFKV LEYLGGSVSN QTDDIMAILL
VEKEGMVKET DIFGWTPLHY AAQLGYLEAT RKLLECDKSV AYLLDKEDSS ALHIAAKKGY
INIMEEITKQ CPCVYNLVDK NGWTILHVAA QCGESKVVKY ILEVRGWESL INEIDNEGNT
ALHLAAIYGH YNSVSILARD GVDKRATNKK YLKAIDIVQT NMDLGEIKKY WIMRKLEDSG
AQQSLERLIV GVNTDEKIND NEGLKEGING LELREDRERI SLDASESFRD RNNEVVKKKD
ITSKYLLKDV SNTHLLVATL IATVTFAACF SLPGGYNQDE PNKGKSVFST KVAFKAFVIT
DGIAFHCSTA AVFLHFFASL EQSYHLHRRR FIKFAALLTY ISLLRMAIAF TSGIFVVLPD
SSLTLTTSIV LGCLFLSFYT FGIL
//
