ID   A5BCE6_VITVI            Unreviewed;      1274 AA.
AC   A5BCE6;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   RecName: Full=Disease resistance RPP13-like protein 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_033712 {ECO:0000313|EMBL:CAN63338.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN63338.1};
RN   [1] {ECO:0000313|EMBL:CAN63338.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM454411; CAN63338.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5BCE6; -.
DR   ExpressionAtlas; A5BCE6; baseline and differential.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1237; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1-RELATED; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
PE   4: Predicted;
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT   DOMAIN          9..97
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          187..404
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   1274 AA;  143942 MW;  1B89F619FA9B79E4 CRC64;
     MEVVGELLLS AAFQVLFDKL ASSDFLTFAR QEHIHSQLKK WETQLFNIRE VLNDAEDKQI
     TSSSVKLWLA DLRNLTYDME DILDEFNTEM LRRKLAVNPQ AAAAAAAATT SKVWSLIPSC
     CTSFTPSHVT FNVSMGSKIK DITSRLEDIS TRKAQLGLEK VAGTTTTTWK RTPTTSLFNE
     PQVHGRDDDK NKIVDLLLSD ESAIVPIVGM GGLGKTTLAR LAYNDDAVVK HFSSRAWVCV
     SDEFDVVKIT KAILGAISQQ SNDSNDFNKL QVELSQSLAG KRFLLVLDDV WNKNYEDWNN
     LRSAFRGGAK GSKVIVTTRN THVALMMEPS VTYHHSLKPL SYDDCWSVFV QHAFENRDIQ
     EHPNLKSIGK KIVEKCDGLP LAAKVLGGLL RSKHRDDEWE HILNSKIWSL PDTECGIIPA
     LRLSYHHLPV QLKRCFVYCA TFPQDYEFKE TELILLWMAE GLIQPLEGNK QMDDLGAEYF
     CELVSRSFFR RSGNGGSRFV LHDLISDLAQ SVAGHLCFNL EDKLEHNKNK IISRDTRHVS
     YNRCYNEIFK KFEAIKEEEK LRTFIALPIY GGPLWCNLTS KVFSCLFPKL RYLRVLSLSG
     YSIKELPNSV GDLKHLQYLN LSRTAIERLP ESISELYNLQ ALILCECGSL AMLPKSIGNL
     VNLWHLDITN AVKLEKMPPH MGNLVNLQTL SKFIVEKNNS SSSIKELKKL SNVVDAQDAM
     DADLKGKHNI KELTMEWGND FDDTRKEENE MQVLELLQPH KNLEKLTISF YGGGIFPSWM
     RNPSFSQMVQ LCLKGCRNCT LLPSLGQLSS LKNLRIQGMS GIKNIGVEFY GQNVESFQSL
     KSLTFSDMPE WEEWRSPSFI DEERLFPRLR ELKMTECPKL IPPLPKVLSL HELKLIACNE
     VVLGRIGVDF NSLAALEIRD CKEVRWLRLE KLGGLKSLTV CGCDGLVSLE EPALPCSLEY
     LEIQGCENLE KLPNELQSLR SATELVIRKC PKLMNILEKG WPPMLRELEV DNCEGIKALP
     GDWMMMRMHG DNTNSSCVLE RVEIWRCPSL LFFPKVVSYP PPLSTSSFRI VGIWNCCRIT
     CPTSHFFILG DVRVSNIITC KTSLLLKHLS ITGCPSLESL REGGLGFAPN LRHVDITDCE
     NLKTPLSEWG LNRLLSLKEL TIAPGGYQNV VSFSHGHDDC HLRLPTSLTS LHIGNFQNLE
     SMASMSLPTL ISLEDLCISD CPKLQQFLPK EGLPATLGRL RIRRCPIIEK RCLKNGGEDW
     PHIAHIPYIV IGRN
//