ID A5BCQ7_VITVI Unreviewed; 1593 AA.
AC A5BCQ7;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN ORFNames=VITISV_032805 {ECO:0000313|EMBL:CAN72235.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN72235.1};
RN [1] {ECO:0000313|EMBL:CAN72235.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
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DR EMBL; AM454757; CAN72235.1; -; Genomic_DNA.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
FT DOMAIN 1355..1465
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 116..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1593 AA; 182718 MW; CD780CD4540D3387 CRC64;
MRKIWPSQDN YIQLKDKFAS CEFGTPTCEI KAYLVKWKWN TVAQSQRSPT CGSDFATCEL
GAQHAKMDSK LRNQLARFSQ GSCNLCMPYW IRDQEGRLVR IENPQDTKLD ICVNIMDPPQ
EDQNSQHGQG GNPNSYLSMR DRMHPPRMSA PSCIVPPLEQ LIIRPHIVPL LPNFHGMESE
NPYAHIKEFE EAKFLKKIFP THRTNGLKRQ ISNFSAKENE KFYECWERYM EAINACPHHG
FDTWLLVSYF YDGMSSSMKQ ILETMCGGDF MSKNPEEAMX FLSYVFEVSR GWDEPNSREM
GRIKAPVNPK GGMYMLSEDM DMKAKVATMA RRPNNNAPYG NTYNSSWRNH PNFSWKPRPP
PYQPQAQTQV PQQTSSVEQA IVNLSKVMGD FMGEQKAIXS QLHQKIENVE SSQIKRMDGM
QNDLSQKVDN IQYSISRLTN LNTVNEKGKF PSQPSQNPKG VHEVETQEGE SSKLREVKVV
ITLRSGKEVD QPLPKVRQDE ELMSRRTLVK ESNNQEEKSG KKNASKSSIE EDPRIVIKED
MMKKHMPPPF PQALHGKKGI KNSSEILEVL RQVKVNIPLL DMIKQVPTYA KILKDLCTVK
RGLNVTKTTF LTEQVSAIIQ CKSLVKYKDT GCPTISVNIG GTHVEKALLD LGASVNLLPY
SVYKQLGLGG LKPTTITLSL ADRSIKIPRR VIEDVLVQVD KFYYPVDFVV LDTDPTVKEA
NYVPIILGRP FLATSNAIIN CRNGVMQLTF GNMTLELNIF HLCKRHLHPK EEEGLEEVCL
INTLVEKHCD KNLEESLNES LGVLEEGRRE EILPLFNKED SQRAATEDPP KLVLKPLPVD
LKYAYLEEDE KCPVVVSSTL TSDQEDSLLG VLKKCKKAIG WKISDLKGIS PLVVRVEVLK
LLQVGIIYPI SDSLWVSPTQ VVPKKSGITV IQNEKEEEVS THYRRLNSVT RKDHFPLPFM
DQVLKRVSGH PFYCFLDGYS GYFQIEIDLE DQEKTTFTCH FDTFAYRRMP FGLCNAPATF
QRCMLSIFSD MVERIMEVFM DDITVYGGSY KECLHLEAVL QRCIEKDLVL NWEKCHFMEV
IKNFSKISKP LCELLVKDAK FVWDEKCQKS FEELKKFLTT TPIVRAPNWK LPFKVMCDAS
DLAMGAVLGQ REDGKPYVIY YASKTLNEAQ RNYTTIEELL AVVFALDKFC AYLVGSFIVV
FTDHSALKYL LTKQDAKARL IRWILLLQEF NLQIRDKKGV ENVVADHLSR LVITHDSHGL
PINDDFPEES LMLIEKRTMK VVQSDFWWPS LFKDAHSMCK GCDRCQRLGK LTRRNMMPLN
PILIVDVFDV WGINFMGPFP MSFGHSYIWS NDHKVVLKFI KVNIFSRFGV PKAIISDRGT
HFCNKPFETL LAKNGVKHKV ATPYHPQTSG QVELANREIK NILMKVVNVN RKDWSIKLLD
SLWAYRTAYK TILGMSPYRL VYGKACHLLV EVEYKAWWAI KKLNMDLTRV GLKRCLDLNQ
LEEMRNDAYL NSKIAKEMLK KWHDQLVNQK NFTKGQRVLL YDSKLHLSLG KLKSRWTGPF
IIHDVQSNGV VELLNFKSTQ TFKVNGHRLK PFI
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