ID   A5BD41_VITVI            Unreviewed;      1429 AA.
AC   A5BD41;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
DE   Flags: Fragment;
GN   ORFNames=VITISV_008274 {ECO:0000313|EMBL:CAN60041.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN60041.1};
RN   [1] {ECO:0000313|EMBL:CAN60041.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- PATHWAY: Amine and polyamine degradation; spermine degradation.
CC       {ECO:0000256|ARBA:ARBA00004723}.
CC   -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC       {ECO:0000256|ARBA:ARBA00005995}.
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DR   EMBL; AM455079; CAN60041.1; -; Genomic_DNA.
DR   ExpressionAtlas; A5BD41; baseline and differential.
DR   GO; GO:0046592; F:polyamine oxidase activity; IEA:UniProt.
DR   GO; GO:0006598; P:polyamine catabolic process; IEA:UniProt.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.90.660.10; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR001613; Flavin_amine_oxidase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR028919; Viral_movement.
DR   PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR   PANTHER; PTHR10742:SF313; POLYAMINE OXIDASE 2; 1.
DR   Pfam; PF01593; Amino_oxidase; 2.
DR   Pfam; PF01107; MP; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   PRINTS; PR00757; AMINEOXDASEF.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          1208..1390
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   NON_TER         1429
FT                   /evidence="ECO:0000313|EMBL:CAN60041.1"
SQ   SEQUENCE   1429 AA;  164551 MW;  FF2A0D1BD9702A04 CRC64;
     MELQIELRTG GMLITKTRVL LASLTAIMAV VFSASSAIAA EEVHAVVIVG AGMSGISAAN
     KLSXAGIENI LILEATNRIG GRIQKTNFAG LSVEIGASWV EGVGGPRLNP IWDMVNRLKL
     TTFYSNYDNI SSNAYKQKGG LYEKSEAQNA FYAAQELSEF IKNVSKVPST PLDMAIDYIA
     YDYEFSEPPR VTSLKNSIPL HTFSKFGEDA YFVADPKGYE SVVYFVAKQF LTTNESGEIT
     DPRLLFNKVV NEISYSKNGV TVKTEDGSVY RAEYVMVSAS IGVLQSGLIN FKPDLPPWKI
     LAMYQFDMAV YTKIFLKFPD KFWPTGNGTE FFFYAHEKRG YYTIWQQLEE EYPGANFLLV
     TVTDDESRRI EQQPDSDTKA EIMGVLRAMF GKNISEATDI LVPRWWSDKF YRGSYSNWPI
     GVSRLEYDRI RAPVGRVYFT GEHTSEYFNG YVHGAYLAET RDGHYCQHLG QRTLRSSDSQ
     DTVVNSEEIN YPKIQNDLDD WKLPNVSNQE IYKKGTFKFF TDYTIKTFEM SVSLEQDDQV
     IRLLDNRSIE KHKRDGYNFI HFGMIQVAAK PLTKLGLNTS IVMCLRDNRH LXYRNSIIGA
     VQAGLNDGPV YFQCYPNFTV RIRDADILDS VVLHIKTHGF KIKPXNXXVS IITRFAYKSM
     NTSVGFRALC TSPKGETTYF HSDMLDKSDF IIPKKILWKD VEFPENWHFV NVVPAIAQRS
     ESIEQIVQYP DGGGELVSPT LSDIPAALEF LFMNPLELQA LPSQLEXLXK KKLTDVRSHT
     NVARPFYTEE NESTQEFQQE ESPVMSPTYS QMINTISLSD EDFEINKDLL RXDFYSEVNK
     QRNDWFFSTV PKVIRTIYQE EFYAYLRQEK KNIKFWIWFE LFKQEEYPNY PCKHINNTST
     KAKIWKTSDN IVIESIHXPK AKIEKNINGT IVTASPFKTK PKDKGTASAI DIRRIMEQIN
     YTNMFLITLG NQVNRVEEII ETQDHLKKSF VKNDNKPLFK PFELSKKFQE NPQIDQAFID
     RISQKDHSDK QEIILKTLTI KDLQEEIGQY KKDIKNLRQP TSSEFPIPHD YINRASFNHN
     SPKKEDFEEV LESSQDNSDK INAYLNTISK VIFQRWEVSL TIVIKNKFIL DIIALIDSGA
     ALNCLQKGLV PTQLYEKTRQ ALFGANGKKL IIKYKLLNAH ICNQGICIKQ TFILVKDLKE
     KALLXDLMDK KLIRKSKSPW SCSAFYVQKQ AELERGTPRL VINYKPLNDV LRWIRYXIPN
     KKDLLQRLVK SKVFSKFDMK SGFWQIQIAE KDKYKTAFVV PFGHYEWNVM PFGLKNAPSE
     FQNIMNEIFN QFSNFIIVYI DDVLIYSDSV EQHWKHLNKF VETVKSNGLS LSATKINLFQ
     TKVRFLGHHI HQGTFTPIQR SIEFADKFPY EIKDKKQLQR FLGSLNYVX
//