ID   A5BDP2_VITVI            Unreviewed;      1291 AA.
AC   A5BDP2;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_025368 {ECO:0000313|EMBL:CAN65521.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN65521.1};
RN   [1] {ECO:0000313|EMBL:CAN65521.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM455674; CAN65521.1; -; Genomic_DNA.
DR   ExpressionAtlas; A5BDP2; baseline and differential.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR013103; RVT_2.
DR   PANTHER; PTHR42648:SF18; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF14223; Retrotran_gag_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF07727; RVT_2; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          482..648
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          736..776
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        736..770
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   UNSURE          925
FT                   /note="I or L"
FT                   /evidence="ECO:0000313|EMBL:CAN65521.1"
SQ   SEQUENCE   1291 AA;  148515 MW;  8385C93F944515F4 CRC64;
     MNEWDTSFNL EMGSFSMGLL LREALVLPIG SKPKSQLKTQ APQAPEAKEI RIELGXDSKC
     APKEEGEKLK MKPKLKWDRG DNEASENNAR AMYSIFNVIS TDEFRRIATC TSAKEAWDIL
     QVTHEGTNVV KVSKLHMLTS RFETIRIEDH ENFGEFHAKL IDIVNSSFNL GEPIPNSKVV
     RKILRSFPER FKAKVIAIEE SKDVDSLKVD ELVGSLQTFE MTLGSPRKSK GIALNAIKEE
     SLGSEGEGNE KMSDGEVARF ARKFKKYMKF KKYKKKSKEE AKKWNNSMGK SNVKDKKKDK
     SVKKDLEVEC FKLLQGGKRV FKRDSNVPHY SGFQXSTSNG MTKVTNVKQI WVKKNELNCL
     VVHIALRASE SHSWYFNNGY SRHMTGNRSF FTNFTEFDGG NVTFGDGNVA SVKGKDTICV
     PGXSNLEEVL LGHLNYHDLM KVANNEVIKG IHNFGKPSNL ICGPCQKRKQ TRSTHKRVNE
     ILTSKPLELL HMDLIGPMRT KSLRGKKYIL VMVDDYSRYA WVAFLRDKSE AFINFKDIGL
     KIQNEKRYPI ERIRSDRGRK FDNYDFLEFC HSLEIKHEFS VPRTPQQNGV VEKKNCVLQE
     MARTMLNQHE LPTHFWAEAI NTVCYTSNRT HMRPHTRKTC YELWKSKKPS VKYFRVFRSR
     CYLLKDHENL GKFESKSEEG IFLGYSSKSR AYRVYILSSK CMVESINVIV DDLGSRSREC
     DEDRIDVSKD IEVIEEKSED EKLSEDEEKK EEQGKKGDRG RIESSKKNKS MVPKNHPLSN
     VIGNYEDIMV TRRQSKLNEV NYVFYTSQIE PKNVEEALND EAWVEALHEE LNQFSRNDVW
     FLVPRPKDVN VIGTKWIFKN KMDENGVIXR NKAXLVAQGF KQIEGIDFDE TFAPVARLES
     ICILLVVACV WKFKLFQMDV KSAFXNGIFN EEVYVEQPKG FQDPRYPNHV YRLRKALYSL
     KQAPRAWHER LTSYLLKKGF MRRGVDRTLF IRRNDEVLLV AQIYVDDIVF GSTFSECALD
     FAKEMKSEFE MSMARELVKK FRLESTKHFR TPMPTNLKLS KDESGKGVDE TLYRSMIGSL
     LYLTASRLDI TFSVGVCARY QACPKESHLI ALKRIIRYIA GTLELGLWYP FDTHSDVACY
     TDADWAGNVD DRKNTSGGCF YIGNCLVVWM SKKQNSISLS IAEAEYIATG SCCSQLLWIK
     QILRDYRIDQ GTIVVFCDNT SVINISKNPV LHSRIKHIDI KHHFICDLVE DKVVLLEYVP
     TEGQIVDILI KPLDVSRFES LRKSIGLCTV N
//