ID   A5BEB6_VITVI            Unreviewed;       685 AA.
AC   A5BEB6;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAN70061.1};
GN   ORFNames=VITISV_025665 {ECO:0000313|EMBL:CAN70061.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN70061.1};
RN   [1] {ECO:0000313|EMBL:CAN70061.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM456463; CAN70061.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5BEB6; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          65..212
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
FT   DOMAIN          276..357
FT                   /note="Reverse transcriptase/retrotransposon-derived
FT                   protein RNase H-like"
FT                   /evidence="ECO:0000259|Pfam:PF17919"
FT   DOMAIN          436..522
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|Pfam:PF13456"
FT   DOMAIN          613..668
FT                   /note="Integrase zinc-binding"
FT                   /evidence="ECO:0000259|Pfam:PF17921"
SQ   SEQUENCE   685 AA;  77864 MW;  17427F213B5DD79E CRC64;
     MKGIHPSITS HRLNVLPTAR PIQQKVRRFH PDRQKIIWNE IDKLIEARFI REVDYTDWLA
     NVVVVPKKEG KWRVCVDYTN LNNACLKDSF PLPRIDQIMD SIAGYHQIPM SPADEEKTAF
     ITPHGLYCYK VMPFVLKNFG ATYQRLMTKI FKPLVGRIVE VYIDDIVVKS KTREEHVLHL
     QEVFQLLRKY DMKLNPSKCA FGVSAGKFLG FMVSQRGIEV SPDQVKAVME TPPPRSKKEL
     QRLTGKLVAL GRFIARFTDE LRPFFLAIRK TGANGWMDSC QNAFKKIKHY LMQLPILSSP
     VPKEKLYMYL AVSEWAISAV LFRYPSPKEQ KPIYYVSRAL ADVETRYSKM ELTTLAFRTH
     PVVVLTDQPL RNILHKPNLT GRMLQWAIEL SEYGIEFQPK LSMKDQVMAD FVLEYSRRPI
     QHKELSEKLW WTLWVDGASR SSGSGVRLLL QSPTGEHLEQ AIRLGFPASN NEAEYEAILS
     GLDFALALSV SKLRVYNDSQ LVVRHVQKEY EAKDARMARY LTKNGRADAL AGIATSLPIK
     EVILLPIHVQ ANPSVAEAST CNTIEASQAN TGTLPEDPKQ AQEIRVQAAN FTLIGGHLYK
     RSFIGPYLRC LNHSEALYVL AELHEGVCGN HSGGRSLAHR VHSQGNYWLT MKKDAAAYVK
     KCDKCQRHAL IPHMSSETLK PISGP
//