ID   A5BKW4_VITVI            Unreviewed;      1051 AA.
AC   A5BKW4;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_027001 {ECO:0000313|EMBL:CAN72447.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN72447.1};
RN   [1] {ECO:0000313|EMBL:CAN72447.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM462989; CAN72447.1; -; Genomic_DNA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR013103; RVT_2.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PANTHER; PTHR42648:SF22; RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON TNT 1-94; 1.
DR   PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF14223; Retrotran_gag_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF07727; RVT_2; 1.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT   DOMAIN          181..196
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50158"
FT   DOMAIN          299..429
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          145..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1051 AA;  120773 MW;  B738E572D5585F58 CRC64;
     MSLMIMKHSI PETISGAIPE ETQANAFLDQ IANQFVANEK VETSTILSKL VSMWYKGKEN
     IREYIMEMSN LVTRLKALKL ELSEDILVHL VLISLPTQFS PFKISYNTQK EKWTLNELIA
     QCVQEEERLK QEKIESAHLA STSQGFGANK KRKRDNKGKQ TAVSKTSKQK VQKKQDKEIT
     CFFCKKAGHM KKTCTKYATW CEKKDTGATT HISVTMQGCL RSRMPTDGER YIYVGNGNKV
     AVKAIGIFKL QIDSRYTLDL EETFEVPSFR RNLISVSCLD KFGYCYSFRN RMCIKGKQTN
     MRKKDVNRCS DVLKLIHTNI CGPFPTTWNG QQYFITFIDD YSRYGYLYLI HEKSQSLDVF
     KNFKAEVENQ LSKKIKAVRS DHGGEYYGRY DGSVEQRPGP FAKYLMECGI VPQYTMPGTP
     SQNGVVERVP SKAVAKTPYE LWTSKKPSIR HLHVWGCPTK ARPYKSNEKK LDFRTVNCYF
     VGYSERSRGF KFYDPSLRSF FEMGNAKFIE DVELSGREPL RKVVFEEEFV SIPMIGYSHI
     MFDDTIQNVQ TITEIQNTPE IPPAQVMEPI QVHEKVTQQP QEPQVQVSLK RSTRERRSTI
     SDDYVVYLQE HEFDMGLEDN PISVSQVKQS SNSEKWIEAM KEEMKSMKDN GVWDLVELPE
     GVKPIGCKWI FKTKRDSKGN IIWYKARLVA KGFTQKEGVD YKETFSPVSS KDSFRIIMAL
     VAHYDLELHQ MDVKTAFLNG NIDEKIYMVQ PKNFESNDSK QLIYRDRPRG ILGLSQKAYI
     DKVWSRFGMS NCAPRDTPXA KGDKFSLHQC PKNELEKKDM ERFPYASAIG SLMYAQVCTR
     PNIAYIVGML GRYLCNXGMD HXKKAKRVMR YLQRTKDYML TYRRSSHLEI VGYXDSDXAG
     CLDSXRSTSG YIFMLAGEAV SWKSVKQTLI ASSTMEAEFI ACYXASNHGI WLXNFITRLR
     IVDGIEKPLR INCDNKAAEF YSKNNRSSSK SKHIDIKFLV VKERVQSLXV SIEHISTNSM
     IADPLTKGLP PKVYHEHXTH MXVVHTXDVL G
//