ID   A5BU81_VITVI            Unreviewed;      1438 AA.
AC   A5BU81;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_012981 {ECO:0000313|EMBL:CAN72700.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN72700.1};
RN   [1] {ECO:0000313|EMBL:CAN72700.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM471327; CAN72700.1; -; Genomic_DNA.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          1162..1322
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   1438 AA;  164021 MW;  ACC26B1FC2F3ED13 CRC64;
     MFLRSLQTRI SRHVVGVHFT DFGSLVSALY DVEDGILRGL WTNSFPSDVK GKKPLGGQRA
     QQTSAPFVLR TQRQFSQLSM PLSQALRKLT EAGLLAALTP RSPPQPIPHQ FRMNLHCAYH
     QGPGHETDRC IALRHAIQDL IDQGLVYLGQ SSVTTNPLPA HTTRVTHPPA DGIHFLEFSD
     RDDYIHMLSW DDTDPEPIMS DGIYEMHGAT LGPQMPVSFK FVPEAASVQA ATVEPLILPH
     YSVQTPFILI PDVEEIVRTY DSTQREVMGT LEIELLIGPA TFVVVFQVLR IPTSFNLLLG
     RPWIHRARTI PSSLHQKVKF IHDDQNFFPS VRPVGIQFGR FSRFIELAER RYFVGEKNRG
     CGASSELRAW RKATTSRFLE VIISVHGSYL AEILSAWLGT TASRIGLVDR VRVHSDGALS
     PSTSVLIASS SLYRTSLMTL CFLDEIDDHE TFVEISDIVD GTAPHDKYVD EMLAMSLSEI
     EEIAPLELAS PFDFFGVSVL KLAEEIQVAP APEIVEDVIL VDGLFDGSVG LVEGASDFVD
     PPLFFDVLLG FVSHHDYVSD SSFMDLSIFE YLPVSCDIDL SAPSSPIAQI FDIDDEIVQH
     DSDNDSSFVS DSDPKLRRLH PCWSLQVNED IQKQLSVGFL SVVEYPEWLA NVVLVPKKDG
     NVRVCVDFLD LNEASPKDDF PFPHIDMLVN STTGHSMLSF MDGFLGYNKI LMALEDMKKT
     SFITEWGTYC YRVMPFGLKN AGATYQRAAT TLFHDMMHRD VEAYVDDMIV KSRERPDHLV
     ALERFFERIQ QFRLRLNPKK CTFGVTSRKL LGYVVSEKGI EVDPNKIRAI LDMPALRMER
     ELDDSGKDRA ICYLSKRMLD YEARYVMIEC YCLALVWVTR RLRHYMTEYS VHLISRLDPL
     RYLFDRPALV GHLMRWLVLL TEFDIHYVTQ KSIRRSIVVD HLVALLVPDG KAIDDDFPDE
     DVADVTSLSG WRMYFDGAAN HSRYGIGILL ISPHGNHIPR SVCLAFSDQH PATNNIVEYE
     ACILGLETAL ELGIRQTEVF GDSNLVSRQI QGEWKTRDVK LRPYHAYLEL LVGRFDDLRY
     TDLPRAQNYV YLEAATAKDR RALRQLATQF VICGETLYRR SVDGMLLLCL DRASTDQVMR
     KRCLECQIHG DLIHVPSSEL HALTSPWPFS VWGIDIIRKI SSKSSSGHEF ILVTIDYFTK
     WVKAASYARL TSSGVASFIR LHIICRYGVL HELIPDRRVH FRAKVDTLVQ RYDIRHHRSF
     AYRPQTNGAV EAVNKNIKRI LWRMVETSRD WSEKLTFALW PYRTSFRTST RATPYSFGIW
     VALEQQIPEV DWAQARFDQL NLLNERRLRA ADHVRAYQRK MAHAFKNRVK PRPLWIGDLV
     LKVIRGLIKD PRGKFRPNWS GPYFIKELTP EGAAWLMDLD GNRFSELTNV NQLKRYYV
//