ID   A5BZM1_VITVI            Unreviewed;       987 AA.
AC   A5BZM1;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAN77422.1};
GN   ORFNames=VITISV_032393 {ECO:0000313|EMBL:CAN77422.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN77422.1};
RN   [1] {ECO:0000313|EMBL:CAN77422.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM476917; CAN77422.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5BZM1; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          46..225
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   DOMAIN          450..579
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   DOMAIN          739..898
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   987 AA;  111790 MW;  B11EF2219BBED0F1 CRC64;
     MKGIHPSIAS HRLNVFSTAR PVRQRIRRFH PDRQRVIRNE IDKLLEAGFI REVSYPDWLA
     NVVVVPKKEG KWRVCVDYTN LNNACPKDSF PLPRIDQIVD STSGQGMLSF LDAFSGYHQI
     PMSPDDEEKT TFITPHDLYC YKVMPFGLKN AGATYQRLMT KIFKPLIGHS VEVYIDDIVV
     KSKTREQHIL HLQEVFYLLR RYGMKLNPSK CAFGVSAGKF LGFMVSQRGI EVSPDQVKAV
     METPPPRNKK ELQRLTGKLV ALGRFIARFT DELRPFFLAI RKAGTHGWTD NCQNALERIK
     HYLMQPPILS SPIPKEKLYM YLAVSEWAIS VVLFRCPSPK EQKPIYYVSR ALADVETRYS
     KMELTALALR SAAQKLRPYF QAHPVIVLTD QPLRNILHKP DLTGRMLQWA IELSEFGIEF
     QPRLSMKGQV MADFVLEYSR KPGQHEESSK KEWWTLRVDG ASRSSGSGIG LLLQSPTGEH
     LEQAIRLGFS ASNNEAEYEA ILSGLDLALA LSVSKLRVFS DSQLVVKHVQ EEYETKDARM
     ARYLAKVRNT LQQFTEWTIE KIKRADNRRA DALAGIAASL LIKEAILLPI HVQTNPSVSE
     ISACNTIEAP QADGQEWMYD ITEYIRTGTL PGDPKQAHKV RVQAARFTLI GGHLYKRSFT
     GPYLRCLGHS EAQYVLAELH EGICGNHSGG RSLAHRAHSQ GYYWPTMKKD ATAYVKKCDK
     CQRYAPIPHM PSATLKSISG PWPFAQWGMD IVGPLPAAPA QKKYLLVATD YFSKWVEAES
     YASIKDKDVT KFVWKNIICR FGIPQTIITD NGPQFDSITF RNFCSELNIR NSYSTPRYPQ
     SNGQAEATNK TLINALKKRL EQAKGRWVEE LPGVLWAYRT TPGRPIGNTP FALAYGMDAV
     IPTEIGLPTI RTDAAKQDDV STELGRNLDW ADEVRENAAI RMADYQQRAS AHYNRKVRPR
     SFKNGTLVLR KVFENTTEVG AGKFQAN
//