ID   A5C1R5_VITVI            Unreviewed;       813 AA.
AC   A5C1R5;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
GN   ORFNames=VITISV_008096 {ECO:0000313|EMBL:CAN75206.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN75206.1};
RN   [1] {ECO:0000313|EMBL:CAN75206.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   EMBL; AM479000; CAN75206.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5C1R5; -.
DR   EnsemblPlants; Vitvi19g04589_t001; Vitvi19g04589_P001; Vitvi19g04589.
DR   EnsemblPlants; Vitvi19g04590_t001; Vitvi19g04590_P001; Vitvi19g04590.
DR   Gramene; Vitvi19g04589_t001; Vitvi19g04589_P001; Vitvi19g04589.
DR   Gramene; Vitvi19g04590_t001; Vitvi19g04590_P001; Vitvi19g04590.
DR   ExpressionAtlas; A5C1R5; differential.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33463:SF190; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT   DOMAIN          247..410
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          108..135
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   813 AA;  93933 MW;  0D0E2E8A3B5CE033 CRC64;
     MPRGVHLTVT SGTHCHPDHP HPSHPHPSLP IKHTWHAFPD CLKEDQTTLI NISSGRLTQY
     IRMINIFHPD TMPWLTKPSE GASGHPVRMS FAATWNTRSA RYQHPENLNS LRTAVEDLKN
     VYEDEKEKVD REEKLRKKRT RAVDGWIQSV EAMEKEVNDL LAKGDEDIQK KCLGTCCPKN
     YRASYNIGKM VHGKMDEVAL KKTEGFNFSV VAEPLPSPTV IERPLDKMQM WRRFSEFFSI
     NWRFLVTWEG RSEDERKEAI FNVLKMKKIV ILLDDIWEPL DLFAVGIPPV NDGSKSKVVF
     TTRFSTVCRD MGAKKRIEVK CLEWAEAFAL FQIHVGEDTI NSHPHLPKLA EIVAKECDGL
     PLALITIGRA MAGVKTPEEW EKKIQMLKNY PAKFPGMENH LFSRLAFSYD SLHDEVVQSC
     FLYCSLFPED YEIDCDRLVQ LWIGEGFLDE YDDIKEARNG GEEIIASLNH ACLLEVNDNI
     DHYLGERARF VKMHDIIRDM ALWLSCQNGN KKQNRFVVVD GGIRRIPMEL RNLKKLRVLI
     LNPMLELREI PSQVISGLSS LQLFSIMDSQ EDIQGDYRAL LEELEGLKCM GEVFISLYSV
     PSIQTLSNSH KLQRCLKILQ VFCPDINLLH LLFPYLEKLV VMHCWKLEDV TVNLEKEVVH
     LTFPRPRYLY HLSEVKIANC ENLMKLTCLI YAPNLKLLNI LDCASLEEVI QVGECGVSEI
     ESDLGLFSRL VLVNLRSLPK LRSICEWSLL FPSLRVMNVV RCPNLRKLPF DSNIKISKNL
     EEIKGEQEWW AELEWEDQTI KHNRTPYFKP QDW
//