ID   A5C5I0_VITVI            Unreviewed;      2267 AA.
AC   A5C5I0;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAN83961.1};
GN   ORFNames=VITISV_011587 {ECO:0000313|EMBL:CAN83961.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN83961.1};
RN   [1] {ECO:0000313|EMBL:CAN83961.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM483055; CAN83961.1; -; Genomic_DNA.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 3.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR005162; Retrotrans_gag_dom.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF03732; Retrotrans_gag; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          1734..1867
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   DOMAIN          1997..2087
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          367..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2267 AA;  256900 MW;  1CF88F573B198A72 CRC64;
     MGEPSPLRNP LGKRGSACVE VMTTLHGSTP SPWRRVEGCV PPEGEFIVTS LDWPSWIRVG
     DRFTKASDQS NQRSDQGDMD SQIVTIDQFA AAMASIQEAI ASLGQRIDGQ QAQQVLVQED
     TQFDTTVPPP PLHSQPAPRT IPFTLHNQTE VAPPPAIVPT PISEDPHARM DKLEQKLRQM
     RTSEGAITWE DFDGAPVASL PAKFRMPEIE RYTGIGCPRI HLRLYSTVMR AHGLDDAQMV
     MLFPMSLSGA AQRWFASLEV SRRRTWDDLA QEFLRQFAFN TVIDVLRREL EALRQRPEES
     VTSFISRWRE KISQIINRPS ERDQISMIMR TLQPRFARHL MGFPHTDFGS LVQALYGIEE
     GIARGLWSES SPTDSKGKRP SGGQRSGDVG AISLVGMRPS RRYQTVGQTL GYYYPPSPHA
     HYRPPTPSRP MTPTYLHPDS QPVFAAHVAE RPPAPYTRPR APQITTYVQR PPRQFAQLGM
     PLSRAFQKLV EGGLLTPLAS RPLPQPIPPR FRMDLHCSYH QGPGHDTDHC TALRHAIQDL
     IDQGLVNLGQ PSVTTNPLPA HSTHAVHPSS GDIHHMDLIE DDSIHMLSWD DGLPKLIVLH
     DSYEVDGVSL VPQTLAPFSL IPDEAPFQLT HPIPLVIRCQ DAFVPFTLWP EDDDSIGREI
     QIMTRSGRIA QPPPPAVRPF EGAASHEEVR REDDEVLRQL QSTQARISIW SLLASSSTHR
     DALIRALSQI RVETTTTLEG LIHMMTASRA TCIVFSDDDL PPDGLDHVHP LYITVGCSGR
     RVPSIQRLSP ECLPFSHCYS PWFRAFRFWS FYSDSQGVLR IPTSFNLLLG RPWIHVAGSI
     PSSLHQKMKF IHDGQVITVS SIRDIFAASE PVLQISHSED DLLLTGFTFD EIQTLEIEDF
     HRDFVAMSFD QHSSTVVLDM MRGMTFLPGM GLGRHQQGPS EFIAAIDHDT TFGLGFIPTE
     ADYRHMARLR KERVRARLSH TPFDYPIRPY RMSLADYFVR GSKTRPHLEE IDSVAHTDRE
     TDLQHLFHQQ QLSDGAPDTS FPMAITPTSP DRASMLSLCF PEEITGDGVM VDSTEMIDGV
     VSHDKYRDEM DMMTMSQITS IVQLQPISAF DMFGVSTIKV FEGTQTLPVP ELPEDDSNLF
     EGIVSPVEGA SDLVDPPLSF DVLSGFVFRF DNYSSVSCDI ISTSAPHSPI TQIFDIDDEI
     AQPSSDKDSF DHDSGPIYER VSPAAGDVET VDFGTEDQPR ELKIGSPLST DERDRLIHLL
     RSYLDVFAWS YEDMPGLDPS IVQHHLPTLP HARLVKQKLR RLHPRWSLQI KEEIQKQLSV
     GFISVVEYPE WLANVVPVPK KDGKVRVCVD FRDLNKASPK DDFPLPHIDL LVDGTAGHSM
     LSFMDGFLGY NQILMAPEDM EKTTFITEWG TYCYRVMPFG LKNARATYQR AATTLFHNMM
     HWDVEVYVDD MIVKSRGRAD HLDALERFFE RIRKFRLRLN PKKCTFGVTF GKLLGHMVSE
     RGIEVDPDKI KAILDMPAPK TEKEIRSFLG RLQYINRFIA RLTDICEPIF RFLRKNQPTV
     WNDDCQFAFE KIKEYLLSPP VLVPPTPGRP LLLYLSVSDM ALGCMLAQID DSGKERAIYY
     LSKRMLKYEM RYVMIERLCL ALVWATRRLR HYMTEYSMDL ISHLDPLRYL FDRPALTGRL
     MRWLVLLTEF DIQYVSQKSI KGSIVVDHLA SLPTSEDRPV DDDFPDEEFV AMTSLSGWCL
     YFDGAANQLG YGIGVLLVSP QGDHIPRSVR LAFHDRHPIT NNIVQYEACI LGLETALELG
     IRQMEVFGDS NLVLRQIQED WKTRDVKLRP YHAYLELLVA RFDDLRYVHM PRAHNRFADT
     LATLASSVDI SIDVVICPLL IESRSGTYPE VATTKDRRAL RNLATRFVIC GDTLYRRSAD
     GMLLLCLDRA SADRVMREVH SGVCGPHMGG HMLARKIMRT GYFWLTMETY CCQFVQKCPE
     CQIHGDLIHA PPSELHALTS PWPFSVWGID IIGKVSPKSS SGHEFILVAI DYFTKWVEAA
     SYARLTSARV ASFIRSHIIC RYGVPHELIS DRGVHFRAET NGAVEAVNKN IKRILRKMAE
     TSRDWSEKLP FALWAYRTSF RNSTGATPYS LVYGMEAVLP IETEMGSLRV ALEQQISDTE
     WAQARFDQLN LLDERRLRAA NHVQAYQRKM AHAFKKRVKP RPLQKGDLVL RILRGLIGDP
     RGKFRPSWSG PYVIRELTLE GAAWLTDLDG NQFSEPTNVD QPKKYYV
//