ID   A5CAY1_VITVI            Unreviewed;       874 AA.
AC   A5CAY1;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAN73244.1};
GN   ORFNames=VITISV_005389 {ECO:0000313|EMBL:CAN73244.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN73244.1};
RN   [1] {ECO:0000313|EMBL:CAN73244.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM488604; CAN73244.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5CAY1; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          381..510
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   DOMAIN          627..742
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   874 AA;  99898 MW;  798ECF001955B727 CRC64;
     MQSALRQNYD IFAWTHSDMK GIDPSITSHK LNKVRRFHPD RQKIIRIEIE KLLEAGFIRE
     WWYPKRKENG GIIRSPCPRN DEEKTAFITP HDLYCYKIMP FGLKNAGATY QRLMTKIFKP
     LIGHTVEVYI DDIVHVLHLR EVFHLLRKYG MKLNPSKCSF GISVGKFLGF MVSQRGIEVS
     SDQVKEVIET PPPRNKKELQ RLTGKLVALG RFIARFTDEL RPFFLAIRKA GTNRWTDNCQ
     NAFEKIKHCL MQPSILSSPI PKEKLYMYLA VSEWAISAVL FRCPSPKEQK PIYYLTALAL
     RSVAQKLRPY FQAHPVVVLT NQPLRNILHK PDLTGRMLQW AIELSEFAIE FQPRLSMKGQ
     VMADFVLEYS RKPSQRQESS EKEWWTLRVD GASRSFGSGV GLLLQSPTGE HLEQAIRLGF
     PASNNEAEYE AILSGLDLAL TLSVSKLRVY SDLQLVVRQV QKEYEAKDAR MTRYLTKLRD
     TLQRFTEWTI EKIRRTENGC ADALAGIAAS LPIKEAILLP IHVQTNPSVA ETSTCNTIEA
     SQADDQEWTN NITEYLWAGT LPGDPKQAHK IRVQAACFTL IGGHLYKRSF IGPYLRCLSH
     SEALYVLAEM HEGVCGNHSR GRSLAHRAHS QGYYWPTMKK DAAAYVKKCD KCQKHAPIPH
     MPKWVEAEAY ASIKDKDVTK FVWKNIICRF GIPQTIITDN SPQFDSIAFR NFCSKLNIQN
     SYSTPRYPQS NGQAEATNKT LMGGPMGGRV TRRPVGLSNH TRAANRKHSL CPRIRYGRNE
     VRESAAIRMA DYQQRASAHY NRKVRPRSFK NGTLVLRKVF ENTAETGAGK FRANWEGPYI
     VSKSNESGAY HLQKLDGTPL LKPWNVSNLK QYYQ
//