ID A5CC53_ORITB Unreviewed; 387 AA.
AC A5CC53;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=2-polyprenyl-6-methoxyphenol 4-hydroxylase {ECO:0000313|EMBL:CAM79218.1};
DE EC=1.14.13.- {ECO:0000313|EMBL:CAM79218.1};
GN Name=ubiH {ECO:0000313|EMBL:CAM79218.1};
GN OrderedLocusNames=OTBS_0152 {ECO:0000313|EMBL:CAM79218.1};
OS Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Orientia.
OX NCBI_TaxID=357244 {ECO:0000313|EMBL:CAM79218.1, ECO:0000313|Proteomes:UP000001565};
RN [1] {ECO:0000313|EMBL:CAM79218.1, ECO:0000313|Proteomes:UP000001565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Boryong {ECO:0000313|EMBL:CAM79218.1,
RC ECO:0000313|Proteomes:UP000001565};
RX PubMed=17483455; DOI=10.1073/pnas.0611553104;
RA Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y.,
RA Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.-S.,
RA Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S., Kim I.-S.;
RT "The Orientia tsutsugamushi genome reveals massive proliferation of
RT conjugative type IV secretion system and host-cell interaction genes.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the UbiH/COQ6 family.
CC {ECO:0000256|ARBA:ARBA00005349}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM494475; CAM79218.1; -; Genomic_DNA.
DR AlphaFoldDB; A5CC53; -.
DR KEGG; ots:OTBS_0152; -.
DR eggNOG; COG0654; Bacteria.
DR HOGENOM; CLU_009665_8_1_5; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000001565; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010971; UbiH/COQ6.
DR NCBIfam; TIGR01988; Ubi-OHases; 1.
DR PANTHER; PTHR43876; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43876:SF7; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CAM79218.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001565}.
FT DOMAIN 1..297
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 387 AA; 43977 MW; F16FEDBAD11F745F CRC64;
MITALGLASY NIKSTIIEKK NLSNTNYLDT RTTALTQRSK SIFKNFNIWK DIEPYISNIN
EVYVVDNKST MMVHLNASKS EFDSIGYMIE NSNLYVKLIE LVQNNPLINV IDNTSYVSID
SHQHSTAIDI NTSSKIHCDL LIVCDGCNSI ARKQYFEYLI DKEYHQSAIV FNVRHQKQHF
GTAVEHFLPN GPFAALPLAD QQVSSIVWVE KSNLATLYAQ MDKKSLTNYV QDKFGCSLGK
IEIITTPVLY PLKAKIAKQY YHNNVVLVGD TAHMIHPLAG QGLNQSIKDI NSLTDILYSR
KSLGLEMTSS EFKLYQRDRF LDNYTMYLLT DNLNRLFSNN LPLLATVRKI SLGLLDKSVI
LKRMIMKYGM GSYSVGSKII NIANYIF
//
