ID A5CU55_CLAM3 Unreviewed; 372 AA.
AC A5CU55;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Inosine-5'-monophosphate dehydrogenase {ECO:0000313|EMBL:CAN02642.1};
DE EC=1.1.1.205 {ECO:0000313|EMBL:CAN02642.1};
GN Name=guaB1 {ECO:0000313|EMBL:CAN02642.1};
GN OrderedLocusNames=CMM_2559 {ECO:0000313|EMBL:CAN02642.1};
OS Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Clavibacter.
OX NCBI_TaxID=443906 {ECO:0000313|EMBL:CAN02642.1, ECO:0000313|Proteomes:UP000001564};
RN [1] {ECO:0000313|EMBL:CAN02642.1, ECO:0000313|Proteomes:UP000001564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 382 {ECO:0000313|EMBL:CAN02642.1,
RC ECO:0000313|Proteomes:UP000001564};
RX PubMed=18192381; DOI=10.1128/JB.01595-07;
RA Gartemann K.H., Abt B., Bekel T., Burger A., Engemann J., Flugel M.,
RA Gaigalat L., Goesmann A., Grafen I., Kalinowski J., Kaup O., Kirchner O.,
RA Krause L., Linke B., McHardy A., Meyer F., Pohle S., Ruckert C.,
RA Schneiker S., Zellermann E.M., Puhler A., Eichenlaub R., Kaiser O.,
RA Bartels D.;
RT "The genome sequence of the tomato-pathogenic actinomycete Clavibacter
RT michiganensis subsp. michiganensis NCPPB382 reveals a large island involved
RT in pathogenicity.";
RL J. Bacteriol. 190:2138-2149(2008).
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM711867; CAN02642.1; -; Genomic_DNA.
DR RefSeq; WP_012039248.1; NC_009480.1.
DR AlphaFoldDB; A5CU55; -.
DR KEGG; cmi:CMM_2559; -.
DR eggNOG; COG0516; Bacteria.
DR HOGENOM; CLU_064068_0_0_11; -.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000001564; Chromosome.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:CAN02642.1}.
FT DOMAIN 16..299
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 372 AA; 39369 MW; 3E87FBD6CC2AA223 CRC64;
MSDVEIGRAK RARRVYAFDD IAIVPSRRTR DPQDVSVTWS IDAYQFEIPF LAAPMDSVVS
PATAIAMGRF GGLGVLDLEG LWTRYEHPER LLEEIRSLPP ESATARMQQI YAEPIKPELI
TARIAEIRAA GVVVAAALSP QRTADHYETV VAAGVDLFVI RGTTVSAEHV SKGAAPLNLK
KFIYELDVPV IVGGAATYTA ALHLMRTGAA GVLVGFGGGA ASTTRSTLGI HAPMATALSD
VAGARRDYMD ESGGRYVHVI ADGGLGSSGD IVKAIAVGAD AVMLGSTLAR ATDAPGQGFH
WGAEAHHSEL PRGHRVRVDQ VAPLEQILYG PSTTADGSAN LVGALRRAMA TTGYSDLKEF
QRVEVVVAPY GK
//
