ID A5CZ17_PELTS Unreviewed; 806 AA.
AC A5CZ17;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Lipid A core-O-antigen ligase and related enzymes {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=PTH_2583 {ECO:0000313|EMBL:BAF60764.1};
OS Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Pelotomaculum.
OX NCBI_TaxID=370438 {ECO:0000313|EMBL:BAF60764.1, ECO:0000313|Proteomes:UP000006556};
RN [1] {ECO:0000313|Proteomes:UP000006556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13744 / JCM 10971 / SI {ECO:0000313|Proteomes:UP000006556};
RX PubMed=18218977; DOI=10.1101/gr.7136508;
RA Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.;
RT "The genome of Pelotomaculum thermopropionicum reveals niche-associated
RT evolution in anaerobic microbiota.";
RL Genome Res. 18:442-448(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP009389; BAF60764.1; -; Genomic_DNA.
DR AlphaFoldDB; A5CZ17; -.
DR STRING; 370438.PTH_2583; -.
DR TCDB; 9.B.67.1.3; the o-antigen polymerase (oap) family.
DR KEGG; pth:PTH_2583; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG3307; Bacteria.
DR HOGENOM; CLU_011929_0_0_9; -.
DR Proteomes; UP000006556; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR007016; O-antigen_ligase-related.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR37422:SF13; SLR1515 PROTEIN; 1.
DR PANTHER; PTHR37422; TEICHURONIC ACID BIOSYNTHESIS PROTEIN TUAE; 1.
DR Pfam; PF13181; TPR_8; 2.
DR Pfam; PF04932; Wzy_C; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006556};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..559
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 588..621
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 806 AA; 88970 MW; 5CBF5160B2CCCA18 CRC64;
MSKAASKPKE KKKAASAPKA REGKKSSEGK KLPEAKKTPR SSEWEFSHAV AFWGLAVLLF
LPPYFRGLFF QPEQERALIF AAVIFWFAWL WKWSKRDHGF LSHPLDYFIL AFPVVYIISA
FQAANYGLAV DEVVKTVLYF LVYWLSSRLI RNERDITAIL QVIYVSAIGV ALAGLSTATG
IIHINDGFLN GRIYSTFQYP NALASYLAAV TFIGIYLWLK AGSTELNIYQ YLYAAGNFLL
LAVLLGTRSN GGLLVFAIVF VLFIAGMPKG NRVSAVIHFI LTGIASFIAI WQFLSAVGSS
KMDMAWLWVF AGLVLTAAGQ ALYSFVVRKG LLDWIAAHKY VVLAAVLLVA VVGCIGAGVY
VSGHAEALKA LAEEVRLRNA TERMYFFQDA LKMFKERPIL GWGGGGWQEA YRAYQSYLYN
SNQVHGHYFQ IMVETGILGL LAILGIWASF LHLAHRLYHG TKADNAARFL VWVIFIAALS
IGLHAAIDFD LSLSALALVL WTMFGLTRSI EIYTRTASEE KKIRKYVPPS NAVLAGASIA
TVVLIVFAGS LAAAGSYAVQ AGKYLQRQNI SQGIALLQKA AAYNPFNADY HSSLARIYQQ
QGKFDEGIAE AQKALELSKY SAPRCADLAS LYFNGKKSSE EAVSYAEKAL SLAPFQVQWY
ELLSRIYFIV GYNEMVSGNR EAAKQYFEKA AAVPGRIEAK MAALNDTEKK LWNVAPLMEP
TPAVKLNVGA SQYLLGRWAE ADAGLQAALS GEKTDEKTKG EAFLWLALLR DKQGRPQEAQ
EYLAQAQKLA PELAKGYEGL RGLKVL
//
