ID A5DDX6_PICGU Unreviewed; 1895 AA.
AC A5DDX6;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=TATA-binding protein-associated factor MOT1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PGUG_01477 {ECO:0000313|EMBL:EDK37379.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK37379.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK37379.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH408156; EDK37379.2; -; Genomic_DNA.
DR RefSeq; XP_001485806.1; XM_001485756.1.
DR STRING; 294746.A5DDX6; -.
DR GeneID; 5127554; -.
DR KEGG; pgu:PGUG_01477; -.
DR VEuPathDB; FungiDB:PGUG_01477; -.
DR eggNOG; KOG0392; Eukaryota.
DR HOGENOM; CLU_000315_1_2_1; -.
DR InParanoid; A5DDX6; -.
DR OMA; WYSDIAC; -.
DR OrthoDB; 180798at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR CDD; cd17999; DEXHc_Mot1; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR044972; Mot1.
DR InterPro; IPR044078; Mot1_ATP-bd.
DR InterPro; IPR022707; Mot1_central_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR36498; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR PANTHER; PTHR36498:SF1; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR Pfam; PF12054; DUF3535; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1306..1479
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1668..1818
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 198..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1840..1865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1895 AA; 211254 MW; 532581809484FDA1 CRC64;
MSRLDRLVVL LETGSTVFIR NTAADQLSDL AKGHPEDAIN LLGRVFPYLK SEKWETRIAA
ARAFGGIVNH CDTWDPNDSD VMKRESEFHD MEMNDPTVKI EDDSERIKQE QDEELQKFDD
NLSNLVDFRS WDLHAILKSG HKLLSSSASD SGVDIEIEDF ESDNLLLKKI KRARIKPEPT
VESRSSLVAP ASLGHTVDNI KSETESVKTE TVSPTPPPMS AAASARLKAM QKRRAKVNAK
SSSGRIKPVD LSQSSMSRKL AEDPDTTDDA VPEPQFDLTS QQGGSKLVME TKDSELSPLL
SQQAKVSGLV WQFQGVYELL LGDLFDPKWE SRHGAALGLR ELMKKHGKGA GRLAKKSRAD
NDRNNSATLE DLAVRLCTLF ALDRFGDYVS DTVIAPVRES AAQTLAALLI HLDEPIVLKT
FDSLYDLVLQ PFADSLNLPK CWEAKHGGML GLRYFVSVKP EIFLSRPDLL DKVIDMVLFG
LKESDDDVQA VAALTLTPIA SEFVETKSAL VHTLLSVIWD CLTNLRDDLS ASIGAVMDLL
ARLCTHTQII DIMQKDAAQD KEKAFENLVP RLFPFLRHSI TNVRKAVLRT ILEFLNIEGP
KVWIDAKTLR LIFQNLLVEQ NREVLDLSMK VFKTTLDVLS SSQPSKITAI FLNHYQPLLS
LLMTPIGIAR HNYNMNTDLI MRPSGHTLDA SEIIDVDSKR GRKRKQEEKN KLDIPTDDLR
VNIDAPIIKG DVMLLGYESF IRTRAAASNA FGLLMSYVED DDLLLELKDV ICGHLKSPHA
TPRLLGAMII QEYADAALQR NVDAHEILQS YSSALMEMLS SSVDLPYFRE LVPTLKSVRT
SCLQLFDTFV TLGKVSQSKL PQLPVLVQGE VDAGPGAFGI ENAEKLINET YEKLTKSMSA
NNRLAANSAL EDSKHRVQVA IDEAKMARSN RIVSILSAYS ASVLAATGIP KKLNPIIRSL
MDSIKQEESE TLQRRAAASV SVLVKQLNEG GKKNASDKIV KNLCAFLCVD TSEIPEVQHN
VKFKTNILSL MKEEAKTDPV DIAAHERAVQ EARIKRTGAM LAMEALINSY STALFDEVPK
LKELMLDPIA LLENTTGDAL IEDQQKGQVV IDALGILRAL LPKLDPSLHD QVLECVPYLK
PGLCSAYSVF RYSSAKALAT ICSVCPTKAF TFLVKSVLPM VNSSGVTEER QGAIESIYHV
SATMGADILP YIVFLIVPVL GRMSDSDHDV RVLATTTFAS IIKLVPLEAG IPDPEGMPQE
LLEGRDKERE FIQQMMDPSK IKPFDLPVSI KATLRKYQQE GVNWLAFLNK YHLHGILCDD
MGLGKTLQTL CIVASDHYLR AEKFKETNSP EFRKLASIII CPPSLTGHWE QEILQYSPFL
KPLVYAGGPS ARAAIRSQIS SADIVITSYD VCRNDIDHLL AHDFNYCVLD EGHIIKNSSS
KLTKSVKQVR AEHRLILSGT PIQNNVLELW SLFDFLMPGF LGTEKVFHEK FAKPIAASRN
SKTSSKEQEA GALALESLHK QVLPFMLRRL KEDVLSDLPP KIIQDYYCEL SELQKTLYKD
FAQKQKNTVQ EEINHRSDGK EGGESNTHVF QALQYMRKLC NHPALVVSPE HPKFNEVNEY
LRINKSDIRS INHAPKLLSL RTLLLECGIG VDDSDYIGKG KNKKSQQQIT AEGVISDHRA
LIFCQLKDML DIVENELLKK HLPSVTYMRL DGSTDPRDRQ SIVRKFNEDP SIDVLLLTTK
VGGLGLNLTG ADTVIFVEHD WNPMNDLQAM DRAHRLGQKK VVNVYRLITK HTLEEKIMGL
QKFKMNIAST VVNQQNSGLA SMDTNQLLDL FDVDEAAAKS TNENSVPERE NYVPEDVKSG
LSGKEAGAVG ELGDLWDEQQ YEDEYNLDNF IKTLK
//
