ID A5DEL7_PICGU Unreviewed; 508 AA.
AC A5DEL7;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=26S proteasome regulatory subunit RPN2 C-terminal domain-containing protein {ECO:0000259|Pfam:PF18004};
GN ORFNames=PGUG_01718 {ECO:0000313|EMBL:EDK37620.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK37620.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK37620.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH408156; EDK37620.2; -; Genomic_DNA.
DR RefSeq; XP_001486047.1; XM_001485997.1.
DR AlphaFoldDB; A5DEL7; -.
DR STRING; 294746.A5DEL7; -.
DR GeneID; 5128118; -.
DR KEGG; pgu:PGUG_01718; -.
DR VEuPathDB; FungiDB:PGUG_01718; -.
DR eggNOG; KOG2062; Eukaryota.
DR HOGENOM; CLU_047628_0_0_1; -.
DR InParanoid; A5DEL7; -.
DR OMA; NTTENAD; -.
DR OrthoDB; 151732at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002015; Proteasome/cyclosome_rpt.
DR InterPro; IPR040623; RPN2_C.
DR PANTHER; PTHR10943; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10943:SF2; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF01851; PC_rep; 1.
DR Pfam; PF18004; RPN2_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..508
FT /note="26S proteasome regulatory subunit RPN2 C-terminal
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002680871"
FT DOMAIN 317..480
FT /note="26S proteasome regulatory subunit RPN2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18004"
FT REGION 366..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 56193 MW; 60B368DB2C936CC8 CRC64;
MLCSTALVLD VVWSAWVAET KTSWKALKVV LYSDSAISGQ AAGLAMGLVM LGSGDQTIAR
DMLTYAQETQ HENIIRGLAI GIALLFYQQE SKALTIVDEL MAQENPILRY GGAFTISLAY
AGTGNNDAIK KLLHYAVSDP SDDVRRASVM GLGFLLIRDY TATPQIVELL SQSHNPHVRY
GAAMALGISC AGRSLPAAID ILEPLTKDSV DFVRQGALMA TSMILIQQNE NLYPKVKEFT
QLYADTVRNK HEDALAKFGA TLSQGIIDAG GRNVTINLEN SHANTLNTSA IVGLTVFAQS
WYWFPFVHFL SLSFSPTSII GVVEDLKVPK FELNCHSRPE LFQYPPKVEE SKEKQPDKVA
TAVLSTTAKA KARARKNKKH EDTEDDKMEV DVLKNEEKET SGDKDEDKKG EEKEIGNEPQ
PIRYLKTPFK IENMSRVLPA QSNYISFVKD DRFVPVRKYR GNAGVIVLRD TKAGEKFEAI
KTVRQLNITE APVPEPFTLS GEDLEDDE
//
