ID A5DFH8_PICGU Unreviewed; 590 AA.
AC A5DFH8;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Protein BZZ1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PGUG_02029 {ECO:0000313|EMBL:EDK37931.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK37931.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK37931.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH408156; EDK37931.2; -; Genomic_DNA.
DR RefSeq; XP_001486358.1; XM_001486308.1.
DR AlphaFoldDB; A5DFH8; -.
DR STRING; 294746.A5DFH8; -.
DR GeneID; 5127695; -.
DR KEGG; pgu:PGUG_02029; -.
DR VEuPathDB; FungiDB:PGUG_02029; -.
DR eggNOG; KOG3565; Eukaryota.
DR HOGENOM; CLU_015390_1_0_1; -.
DR InParanoid; A5DFH8; -.
DR OMA; TPMMEEP; -.
DR OrthoDB; 4260488at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0030864; C:cortical actin cytoskeleton; IEA:UniProt.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:UniProt.
DR CDD; cd11912; SH3_Bzz1_1; 1.
DR CDD; cd11778; SH3_Bzz1_2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035459; Bzz1_SH3_1.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF12; CDC42-INTERACTING PROTEIN 4, ISOFORM B; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 4..270
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 455..515
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 531..590
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 434..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 66747 MW; 073E4DABE75C14EA CRC64;
MASVSIGDEL KDSFKPTLKW VNGGIDWLSD VEEFYRERAT IEKEYAAKLK DLCKRHFEKK
SKIATELSVG KEPKVTPGSL ESASMVLWTD VLTQTEAIAD EKLTLHRELN VKIGDNVVSL
KGKCAKLSRH IESIDEYLTN EKTSTEEELS KARKNYYSVC QSTENVRQKT EKSSSDKYQR
KLSEKEVDMN IAKNQYLLKI NVANRLKDKY YYQDLPELLD YFQEVNEARV AILNKLIKNA
SIVERNSHDR IKEKLHLIDK TVDQNNPTLD TAMFVKHNSF DWKEPEDNYF IPSDIWHDDE
SLVTKEPELT ELKRILNHSS SEFSKYESLA LDTKQKLEEA TIQRHKDQES ITLKFDGSFS
TSLSILQRFM KDDTQRVKSE VEIEVIQNYA GDKDLSHYEE TKKKKSRFGF LKGGKQQGNG
GSDVTSIHTV KSVGSHDKSG FLNLRRNKTK SSMSSSGPTA KALYPYEAAG DDETGMVSGE
VMEILEFDDG SGWTSVKSSG GQGLVPTSYL EILDDGGKKK GPSVPPKRGA KRVQYVEALY
DYQADGDDEI SIRAGDRIAV IQDDTDGSGW TEGEINGERG MFPTSYVKKI
//
