ID A5DS43_LODEL Unreviewed; 1094 AA.
AC A5DS43;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 22-FEB-2023, entry version 78.
DE RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
GN ORFNames=LELG_00179 {ECO:0000313|EMBL:EDK42001.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK42001.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK42001.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH981524; EDK42001.1; -; Genomic_DNA.
DR RefSeq; XP_001527659.1; XM_001527609.1.
DR AlphaFoldDB; A5DS43; -.
DR STRING; 379508.A5DS43; -.
DR GeneID; 5235556; -.
DR KEGG; lel:LELG_00179; -.
DR VEuPathDB; FungiDB:LELG_00179; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_0_2_1; -.
DR InParanoid; A5DS43; -.
DR OMA; GMIMFPI; -.
DR OrthoDB; 204198at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR43310:SF4; SULFATE TRANSPORTER; 1.
DR PANTHER; PTHR43310; SULFATE TRANSPORTER YBAR-RELATED; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 266..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 727..839
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 211..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 856..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1094 AA; 121813 MW; 322476C3DED46416 CRC64;
MSSSHNNLQS DIKATVEENG IQASDKNLVV SPLTTEQQES NLYLSINNKG LESSFDKSLY
NQNHSHSSKN KDRIKRLRNY SIGEAFNYHS NSINNENNNN NNNNNNTINN NNTINNNNFD
IGGRSYVSMS YRPSVSAHIS SPPVKTGVDI HQQTRSLANI GVIDGDDDLE EAFQNEDNHD
NHSLTKPRPI SSNTPLLTDE RALYTIDSQR EQEHDHLKQK ISNTPDDEQQ LQLHEPNRFR
VDSLESFEKA PEPSKIHQLL VKPFQFLPAV FLGLLLNILD GLSYGMIMFP IGEAIFAKLA
PAGLAMFYVS TITSQLIYSL GGSSFKSGIG SEMIEVTPFF HNMALAIAKQ LASEGNDAII
ATTITSFAVS SVITGLTFFA LGYLKLGSLV QFFPRHILIG CIGGVGFFLV ITGIEVSSRL
EGGLFYNYET FQYLFYNHIT LLQWTFPLGL AAGLVALQHR IHNSLLVPLY FIVVFFLFHI
VVALIPSWNL QHARDIGWVF PAVEDDQPWY LFYALYKFDV VDWWCLFRQV PTMLALTFFG
ILHVPINVPA LAITVGMDDI DVDRELVAHG YSNALSGLFG SVQNYLVYTN SVLFIRAGAD
DRLAGVMLAI ATAAVMMAGP VVIGFIPVCV VGALIFLLGY ELLKESVWDT WGRLRPIEYS
TIIIIIVTMG MVDFVVGIGV GIILACVSYV VEAARTPVVQ GIYSGDVARS TVLRHPKQQE
FLKNVGEQIC IVKLQGTIFF GSIGGVEKEI KTIFEIEKAN KVPIKYLILD MKGVVSVDFS
AAEGFRRILN LTNDYRTQLI ISSVKDEDNI IKDLRDAGLF ENSHKIELFN SLNSALEWAE
NQHLKTYKIL KSKHGNDVSG ASTGTGSSTG TSMQSATRAR PAPIANATSV QSPSSFGARL
FGHFGLGDYG TPRTKQVYHA AVKTVDSEHK LQSKYQVTQN DIFKKQPLPL LMITFQGLSQ
KDAEFWSPLA PFFIKEQVPE GIQLYDTNKD EPCLFILESG LIRNTVKFEE GRELDSSIVP
LVAFGDLDEA SQYRRFVYTT VNDSVVWKLS KSKIKEMLKA NGSKGEAIYH ELLEIEAKLI
RERYDVLCSH LVLT
//
