ID   A5EP58_BRASB            Unreviewed;       570 AA.
AC   A5EP58;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=Choline dehydrogenase BetA (CHD)(CDH) {ECO:0000313|EMBL:ABQ37952.1};
DE            EC=1.1.99.1 {ECO:0000313|EMBL:ABQ37952.1};
GN   Name=betA {ECO:0000313|EMBL:ABQ37952.1};
GN   OrderedLocusNames=BBta_6015 {ECO:0000313|EMBL:ABQ37952.1};
OS   Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=288000 {ECO:0000313|EMBL:ABQ37952.1, ECO:0000313|Proteomes:UP000000246};
RN   [1] {ECO:0000313|EMBL:ABQ37952.1, ECO:0000313|Proteomes:UP000000246}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTAi1 / ATCC BAA-1182 {ECO:0000313|Proteomes:UP000000246};
RX   PubMed=17540897; DOI=10.1126/science.1139548;
RA   Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA   Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA   Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA   Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA   Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA   Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT   "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL   Science 316:1307-1312(2007).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR   EMBL; CP000494; ABQ37952.1; -; Genomic_DNA.
DR   RefSeq; WP_012045903.1; NC_009485.1.
DR   AlphaFoldDB; A5EP58; -.
DR   STRING; 288000.BBta_6015; -.
DR   KEGG; bbt:BBta_6015; -.
DR   eggNOG; COG2303; Bacteria.
DR   HOGENOM; CLU_002865_7_1_5; -.
DR   OrthoDB; 9785276at2; -.
DR   Proteomes; UP000000246; Chromosome.
DR   GO; GO:0008812; F:choline dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR012132; GMC_OxRdtase.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00623; GMC_OXRED_1; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU003968};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU003968};
KW   Oxidoreductase {ECO:0000313|EMBL:ABQ37952.1}.
FT   DOMAIN          86..109
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS00623"
SQ   SEQUENCE   570 AA;  62897 MW;  6CEAF93E0F389850 CRC64;
     MPKHEAEFDY VIVGAGSAGC VLANRLTEDP NVKVAILEAG GRNKSLMLRM PAAIGDIFMQ
     KGPANWMFQT VPQGTLDARR LYQPRGRGWG GSSAINGMLY VRGHARDYDQ WRQTGLTGWG
     YADVLPYFKR AEHNENGGDT WRGDRGPLWV SVGPNGNPLY RAFINAGRQA GHPVTRDFNG
     YQQEGLGPFH LTIKDGERCS AASAYLEPAI RDRRNLAVLS HAHAMKIIIE NGEARGVQYA
     SGRMKVVKTV RARREVILSA GVFQSPQLLM LSGIGPADAL RRHGISVVHD APEIGQNLQD
     HFDVVMSYRC TKPITAHSFI TGYRKILLGL EYLLFRTGQG RTNHVQAGAF LKSRTELDRP
     DIQLHFANVM LLNHQPLKTH SHGFGLHVCQ LRPESRGEMR LASPDPFAAP IIDPRYLSSE
     TDRRTIRDGV RMVREIVQQD ALRMYRGPEV HPGLDVQTDS EIDAWTRQTG QSIFHPVGTV
     RMGADANAPV GPDLALRGVR RLRVVDASVM PTLVGGNTNA ATIMIAEKAA DMVRGRPPLS
     REEAPIAEDV AISHRVQVQR FASGTAVAFN
//