ID A5EY09_DICNV Unreviewed; 625 AA.
AC A5EY09;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:ABQ13097.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:ABQ13097.1};
GN Name=ftsI {ECO:0000313|EMBL:ABQ13097.1};
GN OrderedLocusNames=DNO_0987 {ECO:0000313|EMBL:ABQ13097.1};
OS Dichelobacter nodosus (strain VCS1703A).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cardiobacteriales;
OC Cardiobacteriaceae; Dichelobacter.
OX NCBI_TaxID=246195 {ECO:0000313|EMBL:ABQ13097.1, ECO:0000313|Proteomes:UP000000248};
RN [1] {ECO:0000313|EMBL:ABQ13097.1, ECO:0000313|Proteomes:UP000000248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VCS1703A {ECO:0000313|EMBL:ABQ13097.1,
RC ECO:0000313|Proteomes:UP000000248};
RX PubMed=17468768; DOI=10.1038/nbt1302;
RA Myers G.S., Parker D., Al-Hasani K., Kennan R.M., Seemann T., Ren Q.,
RA Badger J.H., Selengut J.D., Deboy R.T., Tettelin H., Boyce J.D.,
RA McCarl V.P., Han X., Nelson W.C., Madupu R., Mohamoud Y., Holley T.,
RA Fedorova N., Khouri H., Bottomley S.P., Whittington R.J., Adler B.,
RA Songer J.G., Rood J.I., Paulsen I.T.;
RT "Genome sequence and identification of candidate vaccine antigens from the
RT animal pathogen Dichelobacter nodosus.";
RL Nat. Biotechnol. 25:569-575(2007).
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DR EMBL; CP000513; ABQ13097.1; -; Genomic_DNA.
DR AlphaFoldDB; A5EY09; -.
DR STRING; 246195.DNO_0987; -.
DR KEGG; dno:DNO_0987; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_6; -.
DR Proteomes; UP000000248; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW Cell cycle {ECO:0000313|EMBL:ABQ13097.1};
KW Cell division {ECO:0000313|EMBL:ABQ13097.1};
KW Glycosyltransferase {ECO:0000313|EMBL:ABQ13097.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022645};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protease {ECO:0000256|ARBA:ARBA00022645};
KW Reference proteome {ECO:0000313|Proteomes:UP000000248};
KW Transferase {ECO:0000313|EMBL:ABQ13097.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 62..242
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 291..586
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 625 AA; 69832 MW; F1089D4A0A8B5ECB CRC64;
MVRPTARSAV RYGQKLRRNI VLAVLVLLAL LLVARLVFLH CIDRPFLLEQ GNNRAMRIRT
EVALRGMILD REGEPLAISS PVSTVVADPK VLWATLEGDF NREKEACLSN SRHSDFCTWI
NDKEIHEDII LMRYEKIRLE PLAAALEMPV GDMMRLLQER AEKRSYYLKR QLSPAQMETV
MALKIHGIFR EDSYQRFYPA GELTGQIIGF TDIDEQGQEG IERQYNDWLS GQQGKVKVLQ
DRDRHAIEIV EETTPVAPGQ NLQLSIDKRL QFIVRKTLSE TMNQFQAKSV SAVMVDVASG
EILAMVSLPD GNPNISVERV AEFMKNKVIT DVFEPGSTIK PISVAAALNA GVITTQTSFK
TSSPYRIGKH TVRDTHNYPQ LDTVGIIRKS SNVGMAMISQ KTPREQYYQF MKQMGFGQLS
GMQFPGEQRG ILHRPEKQDD FTYATTFFGY GISTTALQIA HAYATIANGG VKMPLTLIKR
QHSVEGEQIV SQQIANDVLF MMHEAVNAGG TGRRANTGSY TVAGKTGTAH KITDGRYDRS
RYRGLFAGVA PAQNPKISLI VVVEEPTSGA YYGGLVAAPA FAKIVEWSLP ILGVLPDKIS
RTDDIKLDIQ PQFFAREEKN NENHP
//
