ID   A5FCJ8_FLAJ1            Unreviewed;       727 AA.
AC   A5FCJ8;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Flavodoxin/nitric oxide synthase {ECO:0000313|EMBL:ABQ07077.1};
GN   OrderedLocusNames=Fjoh_4069 {ECO:0000313|EMBL:ABQ07077.1};
OS   Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC
OS   14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=376686 {ECO:0000313|EMBL:ABQ07077.1, ECO:0000313|Proteomes:UP000006694};
RN   [1] {ECO:0000313|EMBL:ABQ07077.1, ECO:0000313|Proteomes:UP000006694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 /
RC   UW101 {ECO:0000313|Proteomes:UP000006694};
RX   PubMed=19717629; DOI=10.1128/AEM.01495-09;
RA   McBride M.J., Xie G., Martens E.C., Lapidus A., Henrissat B., Rhodes R.G.,
RA   Goltsman E., Wang W., Xu J., Hunnicutt D.W., Staroscik A.M., Hoover T.R.,
RA   Cheng Y.Q., Stein J.L.;
RT   "Novel features of the polysaccharide-digesting gliding bacterium
RT   Flavobacterium johnsoniae as revealed by genome sequence analysis.";
RL   Appl. Environ. Microbiol. 75:6864-6875(2009).
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DR   EMBL; CP000685; ABQ07077.1; -; Genomic_DNA.
DR   RefSeq; WP_012026043.1; NZ_MUGZ01000014.1.
DR   AlphaFoldDB; A5FCJ8; -.
DR   STRING; 376686.Fjoh_4069; -.
DR   KEGG; fjo:Fjoh_4069; -.
DR   eggNOG; COG0369; Bacteria.
DR   eggNOG; COG3182; Bacteria.
DR   HOGENOM; CLU_001570_17_4_10; -.
DR   OrthoDB; 9789468at2; -.
DR   Proteomes; UP000006694; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR008333; Cbr1-like_FAD-bd_dom.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR005625; PepSY-ass_TM.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   PANTHER; PTHR19384:SF10; NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1; 1.
DR   PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00970; FAD_binding_6; 1.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   Pfam; PF03929; PepSY_TM; 1.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF52218; Flavoproteins; 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        130..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        172..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          336..475
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50902"
FT   DOMAIN          490..588
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
SQ   SEQUENCE   727 AA;  82130 MW;  95FD070C75C59876 CRC64;
     MTLSFWRYAH LALALFSSIF LLLASVTGII LAVDAVQEKT LPYKAADFDK ITLGETLPVL
     KKEYSEITEL SVDYNQFVTL QAIDKDGNDV NAYIDPKTGK ALGTPAKKSE FIKWVTSFHR
     SLFLHETGRF FVGVISFCLL LISISGFVLV LKRQRGIRNF FSKVIKEYFA QYYHVVLGRL
     ALIPILIIAL TGTYLSLERF NFFMGEEKAK PVKTELSAEA KKTSVFKTTL LSEVKKIEFP
     FTDDPEEYYI IELKDREIEV NQVDGTLLSE KRSPFTVQLS ALSLDLHTGR INTVWAVILA
     IACLNILFFI YSGFAITLKR RSSRIKNKFK ANESNYILLV GSENGSSFRF ANAIAKQLIS
     HGKKVFTAEL NSFSVYPKAE HIIVFSSTHG LGDPPSNARK FKTLLQKQNQ EQKIKFSVVG
     FGSKSYPDFC QFAIEIDQLL ENQNWAERFL DLQTVNDKSA VEFTEWLKLW SGKTEIPLAC
     TPSLYNHVPK GLQKLMVLDK TPISDTEHTF ILTLHANSRT KFASGDLLAV YPANDSRERL
     YSIGNHSGNV QLVVKLHQNG LGSGYLNNLE PGDTIKARII NNHAFHFPKK ASKVAFISNG
     TGIAPFLGMI EQNKAKKEIQ LYSGFRMETP TLLAYKKFAN IMIQKEYLDN FHVALSREAE
     QIYVMDLIKR DTVFFVNLLK DGGVIMICGS LAMQKDVEVI LDELCRDNGM QNLADYKEKG
     QILTDCY
//