ID A5G6Q5_GEOUR Unreviewed; 692 AA.
AC A5G6Q5;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Peptidase S8 and S53, subtilisin, kexin, sedolisin {ECO:0000313|EMBL:ABQ27473.1};
GN OrderedLocusNames=Gura_3316 {ECO:0000313|EMBL:ABQ27473.1};
OS Geotalea uraniireducens (strain Rf4) (Geobacter uraniireducens).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geotalea.
OX NCBI_TaxID=351605 {ECO:0000313|EMBL:ABQ27473.1, ECO:0000313|Proteomes:UP000006695};
RN [1] {ECO:0000313|EMBL:ABQ27473.1, ECO:0000313|Proteomes:UP000006695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rf4 {ECO:0000313|EMBL:ABQ27473.1,
RC ECO:0000313|Proteomes:UP000006695};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Shelobolina E., Aklujkar M.,
RA Lovley D., Richardson P.;
RT "Complete sequence of Geobacter uraniireducens Rf4.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
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DR EMBL; CP000698; ABQ27473.1; -; Genomic_DNA.
DR AlphaFoldDB; A5G6Q5; -.
DR STRING; 351605.Gura_3316; -.
DR MEROPS; S08.130; -.
DR KEGG; gur:Gura_3316; -.
DR HOGENOM; CLU_011263_15_6_7; -.
DR OrthoDB; 9765693at2; -.
DR Proteomes; UP000006695; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07473; Peptidases_S8_Subtilisin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034204; PfSUB1-like_cat_dom.
DR NCBIfam; NF041940; choice_anch_X; 1.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF05345; He_PIG; 2.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49313; Cadherin-like; 2.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000006695};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 141..401
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 149
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 205
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 368
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 692 AA; 72130 MW; 756250BBCB4DA1E8 CRC64;
MSEKWARFVV VLLLVLLVVG KGSAEADTEN GPMRAKFREG ALIVKYKEGV TEETRRHSRE
RHGSVHKREF SGLRMERVGI GQGRTVAEAV KEYEMDDDVE YAEPDYVVRA LVVPNDPRFS
SLWGLSAIAA PAAWDTTTGS SNVVVAVVDT GIDYNHQDIR ANMWVNLAEL NGTPGKDNDG
NGVVGDIYGY NAVKNNGNPL DDNAHGTHVS GTIGAVGNNG IGVTGVNWNT KLMACKFLDA
SGSGYISDAI ECFQYVKGMK ARGANIVATN NSWGGGAYSQ ALYDAINAQR DILFIVAAGN
AGTNNDTTVA YPADYDLPNL IAVAATTSAD GLAGFSNYGR RTVHVGAPGN SILSTVRNNG
YGYMSGTSMA TPHVAGLAAL LKANNSGLDW RGIRSLILST GDQISALNGK SVTGRRINAF
HAVTCQDSRL FSVLKYPARI TVGVPATLSA VSVNCATPAG PVTVSLSGGE VFLLHDDGVA
PDQAAGDGIF ATAYTPTRSS EVFSFSSPAG SETIGNIAPL AVTTSSLPAA TVGSFYSRTL
TASGGVVPYT WNISSGALPA GLSLNSASGT ISGTPTASGN FSFTVRVTDN RGVSAVKTLS
LTVSIATLTI NTTSLPRATH GVYYSVTMAA NGGVRPYTWS ISSGRLPAGL ALNSSSGVIS
GTPTTSGRSS FTVRVTDTRR KTASRNLSIT VN
//
