ID   A5GPF5_SYNPW            Unreviewed;       620 AA.
AC   A5GPF5;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:CAK24820.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:CAK24820.1};
GN   Name=cya1 {ECO:0000313|EMBL:CAK24820.1};
GN   OrderedLocusNames=SynWH7803_2394 {ECO:0000313|EMBL:CAK24820.1};
OS   Synechococcus sp. (strain WH7803).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=32051 {ECO:0000313|EMBL:CAK24820.1, ECO:0000313|Proteomes:UP000001566};
RN   [1] {ECO:0000313|Proteomes:UP000001566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH7803 {ECO:0000313|Proteomes:UP000001566};
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CT971583; CAK24820.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5GPF5; -.
DR   STRING; 32051.SynWH7803_2394; -.
DR   KEGG; syx:SynWH7803_2394; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   HOGENOM; CLU_000445_85_1_3; -.
DR   OrthoDB; 337251at2; -.
DR   Proteomes; UP000001566; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CAK24820.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001566};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        304..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          428..562
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   620 AA;  67354 MW;  CFFC7AC75505EC14 CRC64;
     MKRFRNLLQS TGPYLAAIVV LVLLRSTDLA QTLDLVIYDL ITSQRSEGSG QDQPITLVGI
     EESDIQRFGW PIDDGIFCDA FDALNASGVT AIGFDIYRDQ GVGAEQQCLR DRFREEPTLV
     SIFNVAAGIG AVPGTPIERQ SYNDLSLDGD GVVRRDLVHV TGQDEATVAF PLRVLEVATG
     DRSLRDALDA GTNAGPWLSA DAGGYHNEID AGLGLQRLLR FREPRSYATY TLAEVIDGTV
     PNTMLRDRIV LIGSTAPSLR DLFEVPHTRF ARGDSLFTIS GVEVHANRLA TLIDERNGSF
     QQGWLIPGWG NLLLVIGFAG TGLLLGERIP KQRISILVVG LVAGGAAAGL GALLWNHIWI
     GMAMPLTGLL SFSGAAWLRR GVESQQHSQQ IQQLLGQTTS PAVAQQLWEQ RDSLLSDGRF
     QGQQLPITTL FTDTASFTSV SEGMSPRELM DWLNRGMEIC VPAVTERDGM VNKFTGDGML
     AVFGVPLPGN PSAEAQAAIE AAFQIKDGLE KLNEALKAEG APSMRVRMGI HSGEALVGSM
     GSAERIEYAV IGDAVNCASR LESYDKNRHE GVLRVLLSST TLELLPTEFR ESLHLDYWGP
     VQVKGRDEPL DVSELKFNNE
//