ID   A5H677_9CALI            Unreviewed;       190 AA.
AC   A5H677;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   24-JAN-2024, entry version 51.
DE   SubName: Full=RNA-dependent RNA polymerase {ECO:0000313|EMBL:ABO15288.1};
DE   Flags: Fragment;
OS   Norovirus Hu/GII/NoV750/2004/CAN.
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX   NCBI_TaxID=428117 {ECO:0000313|EMBL:ABO15288.1};
RN   [1] {ECO:0000313|EMBL:ABO15288.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NoV750 {ECO:0000313|EMBL:ABO15288.1};
RA   Pagotto F., Corneau N., Mattison K., Bidawid S.;
RT   "Development of a DNA microarray for the simultaneous detection and
RT   genotyping of Noroviruses.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-
CC         diphosphate + H(+) + phosphate; Xref=Rhea:RHEA:23680,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15;
CC         Evidence={ECO:0000256|ARBA:ARBA00001491};
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DR   EMBL; EF078288; ABO15288.1; -; Genomic_RNA.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.960.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR004004; Helic/Pol/Pept_Calicivir-typ.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001205; RNA-dir_pol_C.
DR   Pfam; PF00680; RdRP_1; 1.
DR   PRINTS; PR00918; CALICVIRUSNS.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000313|EMBL:ABO15288.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT   DOMAIN          2..143
FT                   /note="RNA-directed RNA polymerase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00680"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABO15288.1"
SQ   SEQUENCE   190 AA;  21664 MW;  E48FB52B37377C10 CRC64;
     LSEVTDLSPD IVQANSLFSF YGDDEIVSTD IKLDPEKLTG KLREYGLKPT RPDKTEGPLI
     ISEDLNGLTF LRRTVTRDPA GWFGKLDQSS ILRQLYWTKG PNHEDPFESM IPHSQRPIQL
     MSLLGEAALH EPSFYSKISK LVISELKEGG MDFYVPRQEP MFRWMRFSDL STWEGDRNLA
     PSLVNEDGVE
//