ID A5I203_CLOBH Unreviewed; 690 AA.
AC A5I203; A7G3Q7;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:CAL83067.1};
GN OrderedLocusNames=CBO1526 {ECO:0000313|EMBL:CAL83067.1};
OS Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=441771 {ECO:0000313|EMBL:CAL83067.1, ECO:0000313|Proteomes:UP000001986};
RN [1] {ECO:0000313|EMBL:CAL83067.1, ECO:0000313|Proteomes:UP000001986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger]
RC {ECO:0000313|Proteomes:UP000001986};
RX PubMed=17519437; DOI=10.1101/gr.6282807;
RA Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA White B., Whithead S., Parkhill J.;
RT "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT Hall A and comparative analysis of the clostridial genomes.";
RL Genome Res. 17:1082-1092(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; AM412317; CAL83067.1; -; Genomic_DNA.
DR RefSeq; WP_011949079.1; NC_009698.1.
DR RefSeq; YP_001254036.1; NC_009495.1.
DR RefSeq; YP_001387422.1; NC_009698.1.
DR AlphaFoldDB; A5I203; -.
DR GeneID; 5185781; -.
DR KEGG; cbh:CLC_1559; -.
DR KEGG; cbo:CBO1526; -.
DR PATRIC; fig|413999.7.peg.1503; -.
DR HOGENOM; CLU_000445_107_19_9; -.
DR Proteomes; UP000001986; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001986};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 330..385
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 404..654
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 643..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 566..597
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 690 AA; 76839 MW; 9F0B19B82551D523 CRC64;
MKKNSSIKNK LITSFVSLIL VSLVLLGSIV YTKVYNQTKE DYAQSIEKQI TQVDTSFNNY
IVAFEENIDM FSKGLNNLDK QVTSYVDKKY QLNEIPMTPL KNGSFEASLY KEFENFTKTH
DGIETLSISS ESNGGYMQYP AISRKKGYDP RTRDWYNEAK KNKDKVSFTD VYKTSSGSMV
MSVINPVKDL NSNFKGVMTF DINLKKLSEM SKNTKVGENG YFIVTDEKGT IIASGKDESL
VSKSIKELKV ENLNDLSKYK NSSFSTKMGN GKEYFINVKK SSNEKLGWYY ISFVEKAELT
RSANSIGLIT LILTIMFSIV AVLVCIFISN KISQPIKYAA EHIKEMGKGN FTIPIEEKYF
KLEDEIGDII KSLDRMQNSI KSMLGKVKES SEVVSEEGEK LLSASEEMTG SSSEVSNAIH
DVAVGISNQA GELVKATTTI SSFGERLDMV VGELSSISKN SVSINLVAND SNKKMVNMIV
SVKNIEEFFK DFLNVISKLD NNVGQISEMT NLINSISEQT NLLALNAAIE AARAGESGKG
FAVVADEIRK LAERSKESSE SINKLVENID KDKKDIINNT EKMKEELDSQ SKTIEETIDV
FKNIIEAIED IVPKIQNVNS SAYSINEEKD EVLSKMEGSS AISEEISASS EEISASSEEM
HNCSKDVSIS AEKLSEMTRA MNEEVNKFKI
//
