ID A5JGJ3_HELPX Unreviewed; 256 AA.
AC A5JGJ3;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=hp1117 {ECO:0000313|EMBL:ABQ45809.1};
OS Helicobacter pylori (Campylobacter pylori).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=210 {ECO:0000313|EMBL:ABQ45809.1};
RN [1] {ECO:0000313|EMBL:ABQ45809.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S24 {ECO:0000313|EMBL:ABQ45809.1};
RA Perez C., Ogura M., Dailide G., Berg D., Kalia A.;
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABQ45809.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S24 {ECO:0000313|EMBL:ABQ45809.1};
RA Ogura M., Dailide G., Dailidiene D., Secka O., Ito Y., Lee H.-K., Tan S.,
RA Berg D., Kalia A.;
RT "Geographic subdivision facilitates local adaptations in H. pylori
RT populations.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
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DR EMBL; EF372890; ABQ45809.1; -; Genomic_DNA.
DR AlphaFoldDB; A5JGJ3; -.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR006597; Sel1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR11102:SF147; FIBRONECTIN TYPE-II DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11102; SEL-1-LIKE PROTEIN; 1.
DR Pfam; PF08238; Sel1; 5.
DR SMART; SM00671; SEL1; 5.
DR SUPFAM; SSF81901; HCP-like; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..256
FT /note="beta-lactamase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002683385"
SQ SEQUENCE 256 AA; 28972 MW; 60443F7660979024 CRC64;
MGYASKLALK ICLASLCLFS ALGAEHLEQK RNYIYKGEEA YNNKEYERAA SFYKSAIKNS
EPLAYVLLGI MYENGRGVPK DYKKAAEYFQ KAVDNDIPRG YNNLGVMYKE GKGVPKDEKK
AVEYFRIAAE KGYTNAYINL GIMYMEGRGV PSNYAKATEC FRKAMHKGNV EAYIILGDIY
YSGNDQLGIE PDKDKAIVYY KMAADISSSR AYEGLAESYQ YGLGVEKDKQ KAEEYMQKAC
DFDIDKNCKK KNTSSR
//
