ID A5K4M5_PLAVS Unreviewed; 1562 AA.
AC A5K4M5;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Protein kinase domain containing protein {ECO:0000313|EMBL:EDL45603.1};
GN ORFNames=PVX_091685 {ECO:0000313|EMBL:EDL45603.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45603.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45603.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45603.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45603.1}.
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DR EMBL; AAKM01000005; EDL45603.1; -; Genomic_DNA.
DR RefSeq; XP_001615330.1; XM_001615280.1.
DR STRING; 126793.A5K4M5; -.
DR EnsemblProtists; EDL45603; EDL45603; PVX_091685.
DR GeneID; 5474626; -.
DR KEGG; pvx:PVX_091685; -.
DR VEuPathDB; PlasmoDB:PVX_091685; -.
DR InParanoid; A5K4M5; -.
DR OMA; MNCYFLK; -.
DR PhylomeDB; A5K4M5; -.
DR Proteomes; UP000008333; Chromosome 9.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR045274; WAK-like.
DR PANTHER; PTHR27005:SF78; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR27005; WALL-ASSOCIATED RECEPTOR KINASE-LIKE 21; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EDL45603.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333};
KW Transferase {ECO:0000313|EMBL:EDL45603.1}.
FT DOMAIN 183..551
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 119..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..1005
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1206..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1238..1252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1562 AA; 174893 MW; 12408CBEDEBF55BB CRC64;
MNKKFSPVKE TNIEKGAIDI FKQKIERKKQ SYLRFSFTKS YQNRKGEENR NDGENGSAAC
QNSNAACENG NAACENGNAV CQNSSAACPH NKKVILIQTC DTHDKYILNL HEEECHSCEK
EEKAEEEKEE EETEEEEKKI GNSLPKKTQR KRAHKKEDSV YIPLKILSNK YAYSDIVQAT
NNFAEENKIA KGGNGVVYKG MLKSCISVAI KVLQKNENNG FENEIIIMSR YRHKNILSLL
GYSVNQNYFY LIYEYVHLGD LRTLLFNHYY FYSVRDRENV EVHPACNVQQ GDAEFSPRKK
IPPCGNGSLL MNKQGDPRNG MNNSLRFSLL AHEQFESTQR MPLFLSFSVR LNILIQIINV
LCYLHTSSPI VYHRDLKSAN ILIDEKFNAK LGDFGLSFVY KKNNNVFNLT GGTPGYADPY
YISTHEINEQ TEIYSFGALI LEMLVSKSPA IHVGKNYNCI YNTNDKCPIF CHRKKSENEE
NVFDYLVNHI NMNDYKSIYA VLDHSVHFPE FLVEKLTKLS FLCLNPNIKN RPSSKLVNLI
LLEIQKESEF YIKQQNELVQ KKISCASARL DDNHKGEDSP RVGMQSDGAH KGERGSGNAH
LDGRNEHLEG KNAHREGKNS PRGGGEPRRQ SYPNRRDQIN YDNVKELFFK FIRALFGGDN
ITNDANDAND ANDANDADDL NDGGVDKKLS ADLGIEFYTN LFKAFLDACA ESSLKERVTT
NEERNEEQHI RSPTFKCNTV GNLTQMKNFL FDKLHKDVFF KNNVFNSFSL NLMNCHFARF
IRDYLQECGG ASGLEGSAVE KVAVEKIAAG GAAEDPPGNA TNQLQLGSCA NQKRFGYSPN
ERPFGATPSE HPLGRAAPPC NANESNQQSR APNCGLRRVG PEEDVRSPFN FKRHVQVTPL
RGQPAEGKGS GKGSGNGSGN GIGNGSCNGS CSGGGKNCRM RNKHANEGST FLKQGGEPPG
QAQSRKHDYC PPARIDLMKN GYRAGDPFQR SNHDPGGDPS QRSKLSSTVM HKINGKNKHN
HVDSANVANR SSHQNERPPD IVHPNQQNGT DYEKGNNCHD ANNPVVGRNP QGLCKNGTFG
QMQQGGRNGL ANCEDVLSLY SSPLLQNEKK PQQNTGANKW PLRRNCREGF PQMDLNIAQK
QEEQQPQGVQ DKKVTRVNVA AEEGKAAGSF GARRGGPARG GGFPGGVVVV SAGGLPNGLP
NGLPNGLPNG LPNGLPNGLP NGLPNGLPNG SPSGGRGPHR DNPRDEGGAP QRRGPLENDV
IQICNFANYL SFDRNRSAVD PNAFEWLHKS VFELVIEENK VTSEVTFLDI LYEFNIFTFK
KNHILSNYAT LYGFPLRGDL TESPSPRKYS LSGKWANYGN VENNFITDSS TNEFFFEIAV
HHDFMKKTHT VFLLKSNRSK HQMCSDSQVV LKKTWVSDYV GRRNDFVEQI LKKSISNMLY
ECISRKHCLF LLQVQMRKLK RPTICTDVSG TRREGFSYYL FEYNLRVACN SDNCIFSNNY
ILYKNNVYSY TLPCNTLSLL VFSENQIMKG GGSPGKHSPV TRQVVHFPLY PFFVNINMYS
ER
//
