ID A5KAQ7_PLAVS Unreviewed; 1413 AA.
AC A5KAQ7;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=PVX_001050 {ECO:0000313|EMBL:EDL43656.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL43656.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL43656.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL43656.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL43656.1}.
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DR EMBL; AAKM01000015; EDL43656.1; -; Genomic_DNA.
DR RefSeq; XP_001613383.1; XM_001613333.1.
DR SMR; A5KAQ7; -.
DR STRING; 126793.A5KAQ7; -.
DR EnsemblProtists; EDL43656; EDL43656; PVX_001050.
DR VEuPathDB; PlasmoDB:PVX_001050; -.
DR InParanoid; A5KAQ7; -.
DR OMA; HNEAMER; -.
DR PhylomeDB; A5KAQ7; -.
DR Proteomes; UP000008333; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd10528; SET_SETD8; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR047266; KMT5A-like_SET.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46167; N-LYSINE METHYLTRANSFERASE KMT5A; 1.
DR PANTHER; PTHR46167:SF1; N-LYSINE METHYLTRANSFERASE KMT5A; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1262..1398
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 846..964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..962
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1413 AA; 159984 MW; D94A73409350D407 CRC64;
MKTSTSPPNG FADANVNTSG IGNSNSSGNK RGASKNAFTN AASVIWIERE KLDSIIHIPL
YSDLSKYVSD LGRHPVKQKK KEEEEEKEEK EKEKQGGVLS KIFLLFDDNS CNIAVDISAL
YESENDKIPL LIYERYYFWS LHFLFEKSKI KRQKLNICSD TNGRYGINRL NKYDDDVYMY
TSIYNCAYNR NGDEKNVGGS SYSELGRDNC REVNKELTIY NKDYIKYLYL NDLKNNAMRV
SKSNGGDDAA VGGNAGEAFR GSASSGDPLF EKGLYSNNEI KWYRLKIKIE SVEKKKKNKN
QNLSKGKGGP AGSHPFSFNG YSSCGNYGSC GNYGSCGNYG SCGNYGSCGS GSKTVDAHHN
SNRAFSCEQR PPNNPNGFKK DTHNPTFNAN LMHNVSHLSL IDNDATRKNI NNLIKIQKRS
FFMLNQENGK NVLDTSNDEP LLLSSNRRSE SVFDSSKRES LASCGHQNGK RRKRRNWFYY
KSSSNETNRG LDDDDRSTSR GNSVCALDRG DSYVESKRKG KGEDKGEGNG VDNGVDNRDH
KGDGPFESSS GCDSAGSPSR SRRRTSKKAR SPKGRQPPDG RAKEAAEGVA EEVTEEVAEK
VAEEAAEKVA AKVTAKAAAE IAAEEDSCAN SRMPSESRAY VRTVTAGESG TEFHSFDVEE
EVDAMATAPA VAVDPPEKNQ QKEERQINTN ALFTEETKSP GRLTKNTKVY QENVEEYNSE
FKSIMSEPLN PKEGREKIKR RRDHNRETQM MYLNKILKSI VNKEKSHLNS LSKNFERIEG
FYKQNYKIYI IESKDDLNDK RNCFKSDLHA YVLSPPPSDD ISNELNILDQ FKMYLRRCRG
DYRPRKYQTH ITTGGGKPAG EKPAGEKPVG GGNSGVNLQT NASCTEKKEH SSDNCPGEDH
AGGNAPQKEG EQRGAPMKSS LTKMAPKGKN AEVEDVGETS RSSPQREAGK THPTNQNPPE
NGIIFYAHNK KNPSSVKELR EGDCLYIKFN YSYDDYDKIR VVKKEDLLQI LICLMRNQEC
LKLSHISTYS PDLLWNLSVH FKNNTYDMEL NLEKMYAHFC RRYEVTSPDG RPGLDLQLGF
APLVERAGDH PFGGQSYLPF DVQSHLPFDG QSYIPFDSQL GGQPGCSPEW SPDRWSDRSS
ECSSEAASEA GARASRSFKS AKRAKRENLK EMEIMKLKDY VSFLDKFLQN VNDAKLKRLK
NIQKEYYKKY EFDRSINKLS RQQLLELFVD RKNEMNTIPL SFLKEKSRNI IYEENIKMNM
FACIKITFDE VKGRCIYAAS DLNKFDFVFE YVGELLTHNE AMERERKYNK NKKKGCYMFY
FKHENKRYCI DGTEENIDAA INSKDKKYFL RSFARLVNHS KKNSNLIPKV LTVASLPRLF
FVAARNIKEG EELLIDYGER DREIIKNNEW LKC
//
