ID A5MZE9_CLOK5 Unreviewed; 682 AA.
AC A5MZE9;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Predicted methyl-accepting chemotaxis protein {ECO:0000313|EMBL:EDK34245.1};
GN OrderedLocusNames=CKL_2233 {ECO:0000313|EMBL:EDK34245.1};
OS Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=431943 {ECO:0000313|EMBL:EDK34245.1, ECO:0000313|Proteomes:UP000002411};
RN [1] {ECO:0000313|EMBL:EDK34245.1, ECO:0000313|Proteomes:UP000002411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680
RC {ECO:0000313|Proteomes:UP000002411};
RX PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA Hagemeier C., Thauer R.K., Gottschalk G.;
RT "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT metabolic features.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000673; EDK34245.1; -; Genomic_DNA.
DR RefSeq; WP_012102573.1; NC_009706.1.
DR AlphaFoldDB; A5MZE9; -.
DR STRING; 431943.CKL_2233; -.
DR KEGG; ckl:CKL_2233; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_19_9; -.
DR Proteomes; UP000002411; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002411};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 324..376
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 395..666
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 682 AA; 75185 MW; BCECCC61BCDDD80A CRC64;
MIKIKSIRTR TIITILPVTV MVLIILSVLS YYTGRKIISQ QINRQISYKI NELKLSVNNR
IASHSRIAEV LARTVEISPN TVPEDEYKNL VQKYAAINED TFGVGVWFEP YKYKENIKFF
GPYAYKDSNE VVYTENYMKD DYNYSSQDWY KAGKTTKNKV SWTPPFYDDN TKITMATASA
PFFDGKGNFI GEISADIDLT NLEKMVDEIK FGESGKVFLT TSDGLYIAGV DRKKVMKSKI
TDDSKFSAIS KNILSGKNGN ASYMDGNDKR IIYYTPITST NWVLGITVSQ KELYSPLNSL
VTTLVLLSVL LIIIIAVVIF FYSSYITKNI GQVTKLTSNI CDGDLTYTLN VNSQDELGHM
AQDLNKMSSN LKTTFHSIIH NLDHIVGTSE ELTASAQQTQ TAAEQVAVSI QEVSHHIGLQ
TKETGDISKS VEQIHNGIKN IKENVNLTTQ LSFDSTKIAQ NGSDIMNNVI EQMENISLQV
SESTHVINTL GEKSKEIDSI ITIINSISEQ TNLLALNAAI EAARAGEQGK GFAVVAEEVK
KLAEQSGTAA GKINNIIMEI QQDITSTIIA MNKGNISVDT GKSMVNEASD SFKNIAGSVK
NVSEQMGQIE EVIGGLYGHS DNMVKGVQNI SNVSTKSSNY IENVAAASEE QTALMKQVAG
AAQSLTQIVI ELQSRISEFK VN
//
