ID A5PD94_9SPHN Unreviewed; 503 AA.
AC A5PD94;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Heavy metal RND efflux membrane fusion protein, CzcB family protein {ECO:0000313|EMBL:EDL48214.1};
GN ORFNames=ED21_31724 {ECO:0000313|EMBL:EDL48214.1};
OS Erythrobacter sp. SD-21.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Erythrobacter.
OX NCBI_TaxID=161528 {ECO:0000313|EMBL:EDL48214.1, ECO:0000313|Proteomes:UP000005498};
RN [1] {ECO:0000313|EMBL:EDL48214.1, ECO:0000313|Proteomes:UP000005498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SD-21 {ECO:0000313|EMBL:EDL48214.1,
RC ECO:0000313|Proteomes:UP000005498};
RA Tebo B., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL48214.1}.
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DR EMBL; ABCG01000007; EDL48214.1; -; Genomic_DNA.
DR RefSeq; WP_006834120.1; NZ_ABCG01000007.1.
DR AlphaFoldDB; A5PD94; -.
DR STRING; 161528.ED21_31724; -.
DR eggNOG; COG0845; Bacteria.
DR eggNOG; COG5569; Bacteria.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000005498; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR Gene3D; 2.40.50.320; Copper binding periplasmic protein CusF; 1.
DR InterPro; IPR021647; CusF_Ec.
DR InterPro; IPR042230; CusF_sf.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF11604; CusF_Ec; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005498}.
FT DOMAIN 55..82
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 116..324
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 503 AA; 52657 MW; C0A8482567C90BBF CRC64;
MKAVFERLSP RQRSYAAAAG IALVSLGAGY GLSMLGGGSD GGDAAADTGC EEVLYWYDPM
VPDQRFDEPG KSPFMDMQLV PKCAGGDAQA GEGVSIDSAL VQNFGIRTAE AEYGVLEPET
TVTGTLAYNG SEVAIVQPRA GGYVQRTYGH APQDLIARGA PIVDLLVPEW GGAQQEFLAV
AATGDAALTN AARQRLRLLG MPEGVISSVA RSGRPQSTIT VTAPQSGAIT SLGVRPGMTV
MAGQSLAEIS GYSPIWLEAA VPEALAGSAR VGQPVSATLT AFPGERFAGR IIAILPSAQE
ASRTITVRAA MPNPGLRLKP GMFAQVMIAP ERREALLIPS EAVIRTGERT LVMITQEGGG
YRPAEVRIGR EAGGRTEVLA GLAAGEEVVT SGQFLLDSEA SLAGIDVRSI EDAPTTAGEN
ETQADADEPR TYRATGTIER ITARSITLRH GPVKALDWPA MTMGFATEGP AQVRGFQRGD
RVTFTFVQAS TGPRIVSIRK TGQ
//
