ID A5U3U5_MYCTA Unreviewed; 159 AA.
AC A5U3U5;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Immunogenic protein Mpt63 {ECO:0000313|EMBL:ABQ73695.1};
GN Name=mpt63 {ECO:0000313|EMBL:ABQ73695.1};
GN OrderedLocusNames=MRA_1937 {ECO:0000313|EMBL:ABQ73695.1};
OS Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=419947 {ECO:0000313|EMBL:ABQ73695.1, ECO:0000313|Proteomes:UP000001988};
RN [1] {ECO:0000313|EMBL:ABQ73695.1, ECO:0000313|Proteomes:UP000001988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25177 / H37Ra {ECO:0000313|Proteomes:UP000001988};
RX PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA Wang H., Wang S., Zhao G., Zhang Y.;
RT "Genetic basis of virulence attenuation revealed by comparative genomic
RT analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL PLoS ONE 3:E2375-E2375(2008).
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DR EMBL; CP000611; ABQ73695.1; -; Genomic_DNA.
DR RefSeq; WP_003409684.1; NZ_CP016972.1.
DR AlphaFoldDB; A5U3U5; -.
DR SMR; A5U3U5; -.
DR KEGG; mra:MRA_1937; -.
DR eggNOG; ENOG5030I03; Bacteria.
DR HOGENOM; CLU_067309_1_0_11; -.
DR Proteomes; UP000001988; Chromosome.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR Gene3D; 2.60.40.1240; -; 1.
DR InterPro; IPR029050; Immunoprotect_excell_Ig-like.
DR InterPro; IPR015250; MPT63-like.
DR Pfam; PF09167; DUF1942; 1.
DR SUPFAM; SSF81982; Antigen MPT63/MPB63 (immunoprotective extracellular protein); 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001988};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..159
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002685650"
FT DOMAIN 32..157
FT /note="MPT63-like"
FT /evidence="ECO:0000259|Pfam:PF09167"
SQ SEQUENCE 159 AA; 16514 MW; EB563E1EAABCE428 CRC64;
MKLTTMIKTA VAVVAMAAIA TFAAPVALAA YPITGKLGSE LTMTDTVGQV VLGWKVSDLK
SSTAVIPGYP VAGQVWEATA TVNAIRGSVT PAVSQFNART ADGINYRVLW QAAGPDTISG
ATIPQGEQST GKIYFDVTGP SPTIVAMNNG MEDLLIWEP
//
