ID A5U7F7_MYCTA Unreviewed; 323 AA.
AC A5U7F7;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=NADPH quinone oxidoreductase FadB4 {ECO:0000313|EMBL:ABQ74957.1};
GN Name=fadB4 {ECO:0000313|EMBL:ABQ74957.1};
GN OrderedLocusNames=MRA_3174 {ECO:0000313|EMBL:ABQ74957.1};
OS Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=419947 {ECO:0000313|EMBL:ABQ74957.1, ECO:0000313|Proteomes:UP000001988};
RN [1] {ECO:0000313|EMBL:ABQ74957.1, ECO:0000313|Proteomes:UP000001988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25177 / H37Ra {ECO:0000313|Proteomes:UP000001988};
RX PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA Wang H., Wang S., Zhao G., Zhang Y.;
RT "Genetic basis of virulence attenuation revealed by comparative genomic
RT analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL PLoS ONE 3:E2375-E2375(2008).
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DR EMBL; CP000611; ABQ74957.1; -; Genomic_DNA.
DR RefSeq; WP_003416403.1; NZ_CP016972.1.
DR AlphaFoldDB; A5U7F7; -.
DR SMR; A5U7F7; -.
DR GeneID; 45427128; -.
DR KEGG; mra:MRA_3174; -.
DR eggNOG; COG0604; Bacteria.
DR HOGENOM; CLU_026673_3_1_11; -.
DR Proteomes; UP000001988; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08241; QOR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43677:SF3; PROSTAGLANDIN REDUCTASE 3; 1.
DR PANTHER; PTHR43677; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001988}.
FT DOMAIN 7..319
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 323 AA; 33853 MW; 5AEC3AEA01544C67 CRC64;
MRAVRVTRLE GPDAVEVAEV EEPTSAGVVI EVHAAGVAFP DALLTRGRYQ YRPEPPFVLG
AEIAGVVRSA PDNSQVRSGD RVVGLTMLTG GMAEVAVLSP ERVFKLPDNM TFEAGAGVLF
NDLTVYFALA VRGRLQAGET VLVHGAAGGI GTSTLRLAPA LGASRTVAVV STQEKAELAT
VAGATDVVLA EGFKDAVQEL TNGRGVDIVV DPVGGDRFTD SLRSLAAGGR LLVIGFTGGE
IPTVKVNRLL LNNIDVVGVG WGAWSLTHPD ALAQQWSQLE RLLRSGKLPP PEPVVYPLDQ
AAAAIASLEN RTAKGKVVLR VRD
//
