ID A5UFV2_HAEIG Unreviewed; 616 AA.
AC A5UFV2;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Sialic acid TRAP transporter permease protein {ECO:0000256|RuleBase:RU369079};
DE AltName: Full=N-acetylneuraminic acid permease {ECO:0000256|RuleBase:RU369079};
DE AltName: Full=N-acetylneuraminic acid transporter {ECO:0000256|RuleBase:RU369079};
DE AltName: Full=Neu5Ac permease {ECO:0000256|RuleBase:RU369079};
GN OrderedLocusNames=CGSHiGG_03325 {ECO:0000313|EMBL:ABQ99657.1};
OS Haemophilus influenzae (strain PittGG).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=374931 {ECO:0000313|EMBL:ABQ99657.1, ECO:0000313|Proteomes:UP000001990};
RN [1] {ECO:0000313|EMBL:ABQ99657.1, ECO:0000313|Proteomes:UP000001990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PittGG {ECO:0000313|EMBL:ABQ99657.1,
RC ECO:0000313|Proteomes:UP000001990};
RX PubMed=17550610; DOI=10.1186/gb-2007-8-6-r103;
RA Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C.,
RA Ehrlich G.D.;
RT "Characterization and modeling of the Haemophilus influenzae core and
RT supragenomes based on the complete genomic sequences of Rd and 12 clinical
RT nontypeable strains.";
RL Genome Biol. 8:R103.1-R103.18(2007).
CC -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC transport system. {ECO:0000256|RuleBase:RU369079}.
CC -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC protein and the fused transmembrane protein.
CC {ECO:0000256|RuleBase:RU369079}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU369079}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU369079}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TRAP transporter large permease family and
CC the TRAP transporter large permease family, in different protein ends.
CC {ECO:0000256|RuleBase:RU369079}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000672; ABQ99657.1; -; Genomic_DNA.
DR AlphaFoldDB; A5UFV2; -.
DR KEGG; hiq:CGSHiGG_03325; -.
DR HOGENOM; CLU_019824_4_1_6; -.
DR Proteomes; UP000001990; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR010656; DctM.
DR InterPro; IPR004681; TRAP_DctM.
DR InterPro; IPR007387; TRAP_DctQ.
DR NCBIfam; TIGR00786; dctM; 1.
DR PANTHER; PTHR33362:SF3; SIALIC ACID TRAP TRANSPORTER PERMEASE PROTEIN SIAT; 1.
DR PANTHER; PTHR33362; SIALIC ACID TRAP TRANSPORTER PERMEASE PROTEIN SIAT-RELATED; 1.
DR Pfam; PF06808; DctM; 1.
DR Pfam; PF04290; DctQ; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU369079};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369079};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369079};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369079};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU369079}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 43..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 82..103
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 123..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 152..173
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 193..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 325..352
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 358..380
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 406..425
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 431..449
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 461..483
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 503..520
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 527..549
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 555..574
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 586..607
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT DOMAIN 199..606
FT /note="TRAP C4-dicarboxylate transport system permease DctM
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF06808"
SQ SEQUENCE 616 AA; 67607 MW; AB09EFE2BE377DEB CRC64;
MKYINKLEEW LGGALFIAIF GILIAQILSR QVFHSPLIWS EELAKLLFVY VGMLGISVAV
RKQEHVFIDF LTNLMPEKIR KFTNTFVQLL VFICIFLFIH FGIRTFNGAS FPIDALGGIS
EKWIFAALPV IAILMMFRFI QAQTLNFKTG KSYLPATFFI ISAVILFAIL FFAPDWFKVL
RISNYIKLGS SSVYVALLVW LIIMFIGVPV GWSLFIATLL YFSMTRWNVV NAATEKLVYS
LDSFPLLAVP FYILTGILMN TGGITERIFN FAKALLGHYT GGMGHVNIGA SLLFSGMSGS
ALADAGGLGQ LEIKAMRDAG YDDDICGGIT AASCIIGPLV PPSIAMIIYG VIANESIAKL
FIAGFIPGVL ITLALMAMNY RIAKKRGYPR TPKATREQLC SSFKQSFWAI LTPLLIIGGI
FSGLFSPTES AIVAAAYSVI IGKFVYKELT LKSLFNSCIE AMAITGVVAL MIMTVTFFGD
MIAREQVAMR VADVFVAVAD SPLTVLIMIN ALLLFLGMFI DALALQFLVL PMLIPIAMQF
NIDLIFFGVM TTLNMMVGIL TPPMGMALFV VARVGNMSVS TVTKGVLPFL IPVFVTLVLI
TIFPQIITFV PNLLIP
//
