ID A5UQA3_ROSS1 Unreviewed; 373 AA.
AC A5UQA3;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN OrderedLocusNames=RoseRS_0375 {ECO:0000313|EMBL:ABQ88806.1};
OS Roseiflexus sp. (strain RS-1).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Roseiflexineae;
OC Roseiflexaceae; Roseiflexus.
OX NCBI_TaxID=357808 {ECO:0000313|EMBL:ABQ88806.1, ECO:0000313|Proteomes:UP000006554};
RN [1] {ECO:0000313|Proteomes:UP000006554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS-1 {ECO:0000313|Proteomes:UP000006554};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.;
RT "Complete sequence of Roseiflexus sp. RS-1.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU362026}.
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DR EMBL; CP000686; ABQ88806.1; -; Genomic_DNA.
DR RefSeq; WP_011955163.1; NC_009523.1.
DR AlphaFoldDB; A5UQA3; -.
DR STRING; 357808.RoseRS_0375; -.
DR REBASE; 15589; M.RspRSORF375P.
DR KEGG; rrs:RoseRS_0375; -.
DR eggNOG; COG2189; Bacteria.
DR HOGENOM; CLU_024927_5_1_0; -.
DR OrthoDB; 9800801at2; -.
DR Proteomes; UP000006554; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR040843; RAMA.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR Pfam; PF18755; RAMA; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ABQ88806.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 37..258
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT DOMAIN 274..370
FT /note="RAMA"
FT /evidence="ECO:0000259|Pfam:PF18755"
SQ SEQUENCE 373 AA; 42900 MW; C105C1B7AD5CBBFA CRC64;
MQPQAWVDER NTSQLPVNEI IQGDCVEVLK TFPAKSVDLI FADPPYNLQL RNQLLRPNQT
VVDGVDDEWD QFANVAEYDA FTRNWLSACR RVLKDDGTIW VIGSYHNIFR IGTIMMDLGY
WILNDVIWYK TNPMPNFRGT RFQNATETLI WAKKSVEQKK YTFNYHAMKH LNDEKQMQNV
WHIPLCTGPE RIKLNGKKVH STQKPEALLY RVILASSNPG DVVLDPFFGS GTTGAVAKKL
KRNYIGIELE PAYIDIARKR IDTLPMSLLD ETELVTPSKR TVPRVSFGQL IESHYITVGQ
KVFSKDRKVV ATVKADSHLL WGNVTGSIHR IAALAQNKPA FNGWEYWYCE DQEGNVISID
ALRERYRIEH NLE
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