ID A5UXW8_ROSS1 Unreviewed; 362 AA.
AC A5UXW8;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Cobalamin synthesis protein, P47K {ECO:0000313|EMBL:ABQ91471.1};
GN OrderedLocusNames=RoseRS_3108 {ECO:0000313|EMBL:ABQ91471.1};
OS Roseiflexus sp. (strain RS-1).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Roseiflexineae;
OC Roseiflexaceae; Roseiflexus.
OX NCBI_TaxID=357808 {ECO:0000313|EMBL:ABQ91471.1, ECO:0000313|Proteomes:UP000006554};
RN [1] {ECO:0000313|Proteomes:UP000006554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS-1 {ECO:0000313|Proteomes:UP000006554};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.;
RT "Complete sequence of Roseiflexus sp. RS-1.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP000686; ABQ91471.1; -; Genomic_DNA.
DR RefSeq; WP_011957815.1; NC_009523.1.
DR AlphaFoldDB; A5UXW8; -.
DR STRING; 357808.RoseRS_3108; -.
DR KEGG; rrs:RoseRS_3108; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_1_1_0; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000006554; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF65; 47 KD PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 247..339
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 219..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 40133 MW; E0D1DE8DD29DE67C CRC64;
MSIEAPLRPV PVTILTGFLG AGKTTLLNRI LHADHGLRVA VLVNDFGSIN IDTQLVVGVE
GETISLANGC ICCSIRGDLL KTALLLLDRE EPPEYLIIEA SGVSDPWAVA ETFDLPELRP
FFHLDSVITV VDVEYVRKQQ YYEDLIIHQI SAADVVVLSK VDLVSAEQRA DVEQWVRQIV
PRARILPAIH GDVPMSLLLG VGRYKLDVQP PVVSRLHAHD HDHEHGPHCD HDHDHDHEHH
HDHTTEFSSW SYVNHRPFAL KKLRTVLQDL PETIFRAKGI IYLAETPGRR AILQIVGVRI
TVSVGEPWGD TPPGTQMVFL GIPGGLNGDA LQKAFDSCLT DVPAQEQVVG QQSWFRRVFG
GA
//
