ID   A5WCC9_PSYWF            Unreviewed;       319 AA.
AC   A5WCC9;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   RecName: Full=HTH-type transcriptional regulator MetR {ECO:0000256|ARBA:ARBA00019365};
DE   Flags: Precursor;
GN   OrderedLocusNames=PsycPRwf_0365 {ECO:0000313|EMBL:ABQ93320.1};
OS   Psychrobacter sp. (strain PRwf-1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Psychrobacter.
OX   NCBI_TaxID=349106 {ECO:0000313|EMBL:ABQ93320.1};
RN   [1] {ECO:0000313|EMBL:ABQ93320.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PRwf-1 {ECO:0000313|EMBL:ABQ93320.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome of Psychrobacter sp. PRwf-1.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; CP000713; ABQ93320.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5WCC9; -.
DR   STRING; 349106.PsycPRwf_0365; -.
DR   KEGG; prw:PsycPRwf_0365; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_0_6; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd08441; PBP2_MetR; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037406; MetR_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR30126:SF25; HTH-TYPE TRANSCRIPTIONAL REGULATOR METR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          2..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   319 AA;  35537 MW;  9CB8B7D8432E57F1 CRC64;
     MLELRHLQTL TALRAHGSLA AAADELHVTA SAVSHQLKEL ENYYGVKLVN RRTRPLTFTP
     AGKVVLKLAD SILPQVTRTK NNLKRLAHGQ AGRLRLASEC HSCFDWLMPI LNQFRREWSD
     VELDFATGFE PEPHHLLSEG DIDLLITTSD LDIEGICYQP LFSYESRLVL SPTHPLASKT
     SIVPDDLVDQ TLIAYPVETK RLDVIAKFMA PAEASFAKIR TTELTAMLIQ LVASERGVAA
     LPDWVAAEYE KKGWVVTRPF VAPEGSDNRL NPITHPSSRA HSLPKTGIYC QLFAATRQSS
     QDTAYMQGFA KLLEELVKP
//