ID   A5X3M9_ORYNI            Unreviewed;       576 AA.
AC   A5X3M9;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   03-APR-2013, entry version 29.
DE   SubName: Full=Polyphenol oxidase;
GN   Name=PPO;
OS   Oryza nivara (Indian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=4536;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=G12;
RX   PubMed=19033526; DOI=10.1105/tpc.108.060426;
RA   Yu Y., Tang T., Qian Q., Wang Y., Yan M., Zeng D., Han B., Wu C.I.,
RA   Shi S., Li J.;
RT   "Independent Losses of Function in a Polyphenol Oxidase in Rice:
RT   Differentiation in Grain Discoloration between Subspecies and the Role
RT   of Positive Selection under Domestication.";
RL   Plant Cell 20:2946-2959(2008).
CC   -!- COFACTOR: Binds 2 copper ions per subunit (By similarity).
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DR   EMBL; DQ532410; ABG23077.1; -; Genomic_DNA.
DR   ProteinModelPortal; A5X3M9; -.
DR   SMR; A5X3M9; 82-423.
DR   Gramene; A5X3M9; -.
DR   GO; GO:0004097; F:catechol oxidase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046148; P:pigment biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; -; 1.
DR   InterPro; IPR016213; Polyphenol_oxidase.
DR   InterPro; IPR022740; Polyphenol_oxidase_C.
DR   InterPro; IPR022739; Polyphenol_oxidase_cen.
DR   InterPro; IPR002227; Tyrosinase.
DR   InterPro; IPR008922; Unchr_di-copper_centre.
DR   Pfam; PF12142; PPO1_DWL; 1.
DR   Pfam; PF12143; PPO1_KFDV; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PIRSF; PIRSF000290; PPO_plant; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper_centre; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   3: Inferred from homology;
KW   Copper; Disulfide bond; Metal-binding.
FT   METAL       171    171       Copper A (By similarity).
FT   METAL       192    192       Copper A (By similarity).
FT   METAL       201    201       Copper A (By similarity).
FT   METAL       323    323       Copper B (By similarity).
FT   METAL       327    327       Copper B (By similarity).
FT   METAL       357    357       Copper B (By similarity).
FT   DISULFID     92    108       By similarity.
FT   CROSSLNK    175    192       2'-(S-cysteinyl)-histidine (Cys-His) (By
FT                                similarity).
SQ   SEQUENCE   576 AA;  63288 MW;  01FE70B1E86E2188 CRC64;
     MESINVAPGT TATPRMAPPP PPPCITNLQS TLRYNNLLLH RKTKGWKPRN VSCRVDRRDV
     LLGISGAAAM VATQGGGGAL AAPIQAPDLG DCHQPVDVPA TAPAINCCPT YSAGTVAVDF
     APPPASSPLR VRPAAHLADR AYLAKYERAV SLMKKLPADD PRSFEQQWRV HCAYCDGAYD
     QVGFPGLEIQ IHSCWLFFPW HRMYLYFHER ILGKLIGDET FALPFWNWDA PDGMSFPAIY
     ANRWSPLYDP RRNQAHLPPF PLDLDYSGTD TNIPKDQLID QNLNIMYRQM ISGARKAELF
     MGQPYRAGDQ PEPGAGTVES VPHNPVHRWT GDPRQPNGED MGIFYSAARD PVFFAHHGNV
     DRMWHIRRGL LFPGDTDFTD PDWLDASFFF YDEEARLVRV RVRDTLDPSA LRFTYQDVGL
     PWLNAKPSTG AASTPAPAAG AFPATLDKTV RVAVTRPRAS RSREEKEEEE EVLVIEGIEI
     PDHSTYVKFD VFVNAPESGD GAATCAATCA GSVALAPHGI HREGQLSPRK TEARFGICDL
     LDDIGADGDK TIVVSIVPRC GCDSVTVAGV SIGYAK
//