ID A5YT84_PETMA Unreviewed; 325 AA.
AC A5YT84;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=AMP-activated protein kinase gamma B {ECO:0000313|EMBL:ABQ59298.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|EMBL:ABQ59298.1};
RN [1] {ECO:0000313|EMBL:ABQ59298.1}
RP NUCLEOTIDE SEQUENCE.
RA Grignani R., Pinter K., Farza H., Khor C.C., Carballo S., Ling E.,
RA Paterakis P., Grignani D., Peden J., Watkins H.;
RT "Differential expression of AMPK gamma isoforms in vertebrate development
RT and evolution: A mechanism for phenotype.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1
CC or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic
CC subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
CC {ECO:0000256|ARBA:ARBA00025878}.
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase gamma
CC subunit family. {ECO:0000256|ARBA:ARBA00006750}.
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DR EMBL; EF584739; ABQ59298.1; -; mRNA.
DR AlphaFoldDB; A5YT84; -.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd04618; CBS_euAMPK_gamma-like_repeat1; 1.
DR CDD; cd04641; CBS_euAMPK_gamma-like_repeat2; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF35; LD22662P; 1.
DR Pfam; PF00571; CBS; 3.
DR SMART; SM00116; CBS; 4.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
PE 2: Evidence at transcript level;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Kinase {ECO:0000313|EMBL:ABQ59298.1};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Transferase {ECO:0000313|EMBL:ABQ59298.1}.
FT DOMAIN 34..94
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 116..176
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 189..251
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 263..320
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 325 AA; 37308 MW; A6A4F180F15DE5EC CRC64;
MLETLHWYED QAEEGEESVY SRLMKAQCCY EVIPTSSKLV VFDISLQVKK AFFALVDSGV
RAAPLWDSKL QTFVGMLTIT DFINILHRYY KSPMVQIYEL EEHKIETWRE VYLQDSFKPL
VSITPEASLF DAVYSLIKNK IHRLPIIDPV SGNVLYILTH KRILRFLHLF ISELPKPRFM
CRPLGELRVG TFNDIAFIYT DTPIITALNL FVERRVSALS VVDRSGRVVD VYSKFDVINL
AAEKNYNNLD MTVTQALHHR SQYFEGVVKC RRHESLETIV GRLVHAEVHR VVVVDENDRV
VGILSLSDYL QALILTPAGV DALNS
//
